Narra J
Vol. 1 No. 3 (2021): December 2021

Correlation of neutrophil-to-lymphocyte ratio and clinical outcome of acute thrombotic stroke in patients with COVID-19

Rizky Sarengat (Department of Neurology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
Department of Neurology, Dr. Soetomo General Hospital Surabaya, Indonesia)

Mohammad S. Islam (Department of Neurology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
Department of Neurology, Dr. Soetomo General Hospital Surabaya, Indonesia)

Mohammad S. Ardhi (Department of Neurology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
Department of Neurology, Dr. Soetomo General Hospital Surabaya, Indonesia)



Article Info

Publish Date
01 Dec 2021

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has caused millions of deaths worldwide. Acute ischemic stroke is a life-threatening risk factor for COVID-19 infection. Neutrophil-to-lymphocyte ratio (NLR) is one of the predictors of poor prognosis in acute ischemic stroke. The aim of this study was to assess the correlation between NLR values and the clinical outcome of acute thrombotic stroke patients with COVID-19 that was measured using the National Institutes of Health Stroke Scale (NIHSS). A cross-sectional hospital-based study was conducted in Dr. Soetomo General Hospital Surabaya, Indonesia. Patients with acute thrombotic stroke and COVID-19 admitted between 1 March 2020 and 31 May 2021 were recruited. The NLR values and the NIHSS scores were assessed during the admission and the correlation between NLR and NIHSS scores was calculated. This study included 21 patients with acute thrombotic stroke and COVID-19, consisting of 12 males and 9 females. The mean age was 57.6 years old. The mean NLR values was 8.33±6.7 and the NIHSS scores ranging from 1 to 33. Our data suggested a positive correlation between NLR values and NIHSS scores, r=0.45 with p=0.041. In conclusion, the NLR value is potentially to be used as a predictor of the clinical outcome in acute thrombotic stroke patients with COVID-19. However, further study is warranted to validate this finding.

Copyrights © 2021






Journal Info

Abbrev

main

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Narra J is a multidisciplinary journal and it is published three times (April, August, December) a year. The objective is to promote articles on infection, public health, global health, tropical infection, one health and diseases in tropics. Narra J publishes original research work across all ...