Bioscientia Medicina : Journal of Biomedicine and Translational Research
Vol. 6 No. 5 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research

Differences Post Delivery of Term Pregnancy Mean Maternal Serum Magnesium Level with Low Versus Normal Birth Weight

Dovy Djanas (Fetomaternal Division, Obstetrics and Gynecology Department, Medical Faculty, Andalas University, Padang, Indonesia)
Heri Farnas (Department Obstetrics and Gynecology, Medical Faculty of Andalas University, Padang, Indonesia)
Roza Sriyanti (Fetomaternal Division, Obstetrics and Gynecology Department, Medical Faculty of Andalas University, Padang, Indonesia)
Syntia Ambelina (Department Obstetrics and Gynecology, Bunda General Hospital, Padang, Indonesia)



Article Info

Publish Date
10 Mar 2022

Abstract

Background. Impaired fetal growth is still a major problem in obstetrics. Birth weight is usually used as an indicator of the well-being of the newborn and as an indirect measure of intrauterine nutrition during pregnancy and the mother's nutritional status during pregnancy. Magnesium contribute as a cofactor for various enzymes in the human body for metabolic processes. Fetal magnesium is obtained from maternal by transport through the placenta. In conditions of low magnesium levels will affect the epigenetic process, HPA-axis and GH-IGF axis of the fetus which in turn will result in fetal growth disorders. This study aims to determine the differences postdelivery serum magnesium levels of women at term pregnancy who give birth with low vs normal birth weight. Methods. This study used an observational analytic method with a cross sectional approach. Conducted from April 2020-December 2020 at Dr. M. Djamil Padang Central General Hospital and Network Hospital Faculty of Medicine, Andalas University. Total of 44 samples were divided into 2 groups, women who gave birth with low and normal birth weight babies. Samples was carried out at the Pramitha Padang Private Clinical Laboratory. Results: The mean maternal serum magnesium level in low birth weight group was 1.97 ± 0.16 mg/dL lower than normal birth weight group was 2.06 ± 0.14 mg/dL. Statistic test using the independent sample T test showed no differences in both groups (p = 0.064). Conclusion. The mean maternal serum magnesium level in low birth weight 1.97±0.16 mg/dL. The mean maternal serum magnesium level in normal birth weight was 2.06 ± 0.14 mg/dL. There was no significant difference on both groups.

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Journal Info

Abbrev

bsm

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

Description

BioScientia Medicina is an open access international scholarly journal in the field of biomedicine and translational research aimed to publish a high-quality scientific paper including original research papers, reviews, short communication, and technical notes. This journal welcomes the submission ...