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All Journal Indonesian Journal of Obstetrics & Gynecology Science Journal of Midwifery Bioscientia Medicina : Journal of Biomedicine and Translational Research Andalas obstetrics and gynecology journal Science Midwifery Bioscientia Medicina : Journal of Biomedicine and Translational Research

Yanti, Roza Sri

Sub Division Of Maternal Fetal Medicine, Obstetrics And Gynecology Department, Faculty Of Medicine, Andalas University, Dr. M. Djamil Central General Hospital Padang

Author-ID : 2746030

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Differences of Magnesium Level Between Normal Pregnancy and Preeclamsia Rengga Pradipta; Roza Sriyanti; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.63-68.2021

Background: Preeclampsia is a multi-organ disorder that occurs in pregnant women with high blood pressure which is still difficult to predict. Until now, many theories have put forward the causes of preeclampsia, one of which is much debated is the lack of nutrition in pregnant women which can lead to preeclampsia. Several studies suggest that there is a relationship with the lack of micronutrient intake, especially magnesium, which causes preeclampsia, especially in developing countries. Magnesium deficiency is one possible factor causing severe preeclampsia. Magnesium plays a role in normal neuromuscular function, regulation of calcium, potassium and transport of sodium in the membrane as a regulation of the activation of ATP. Magnesium also plays a role in blood pressure regulation. Magnesium deficiency can lead to endothelial malfunction, hypertension and failure of the cardiovascular system. The role of magnesium is in enzyme reactions that bind to anaerobic glucose metabolism, the krebs cycle, fatty acid oxidation and reactions between coenzyme and fatty acids. Magnesium deficiency will result in changes to the nerves, muscles and blood vessels.Methods: Analytical observational study with cross sectional design in 17 women with preeclampsia and 17 normal pregnant women who met the inclusion and exclusion criteria. Research subjects were collected at Dr M Djamil Padang General Hospital, November 2019 to January 2020. Magnesium levels were checked by enzymatic methods. The difference in the mean magnesium preeclampsia and normal pregnancy was analyzed using independent t test.Results: Mean magnesium in preeclampsia was lower than normal pregnancy (1.61 ± 0.59aµg / ml vs 2.20 ± 0.18, p = 0.001).Conclusion: Mean magnesium level in preeclampsia was significantly lower than normal pregnancy..Keywords: Average levels of magnesium, magnesium, preeclampsia, normal pregnancy

MODE OF DELIVERY DOES NOT CORRELATE FETAL OUTCOME IN PREGNANCY WITH COVID-19 AT DR. M. DJAMIL HOSPITAL PADANG Heri Farnas; Roza Sriyanti
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.42-49.2022

Introduction: Corona Virus Disease 2019 (COVID-19) was first reported in Wuhan, China. Knowledge about COVID-19 infection in relation to pregnancy and the fetus is still limited. Report from China shows high rate of caesarean delivery (> 90%) due to the suspicion for vertical transmission. Globally there is an increase of caesarean delivery in women with COVID-19 infection. Clinical implications mode of delivery in pregnancies with COVID-19 infection are not fully understood.Objective: The aims of this study to assess differences in fetal outcome based on the mode of delivery in pregnancies with COVID-19 infection.Methods: This observational analytic study with cross sectional study design was conducted in single center at dr. M. Djamil General Hospital Padang from March 2020-March 2021. All study subjects qualified to inclusion and exclusion criteria included. The fetal outcome analyzed based on APGAR scores and COVID-19 status in newborn baby using Mann-Whitney test.Results: A total of 49 patients were analyzed. The results showed mean APGAR score 1 minute in the vaginal delivery was lower than caesarean delivery (6.87±1.06 vs 7.38±0.82) but not significant (p=0.09). No significant difference between vaginal delivery and caesarean delivery based on APGAR score 5 minutes (p=0.19). None newborn babies infected with COVID-19 in both groups.Conclusions: There was no difference of fetal outcome based on the APGAR score in pregnancies with COVID-19 infection by mode of delivery. There were no cases of infants with COVID-19 infection in both groups.Keywords: COVID-19, mode of delivery, APGAR score

Thanatophoric Dysplasia Tria Sari Retno Asih; Roza Sriyanti
Andalas Obstetrics And Gynecology Journal Vol 3, No 2 (2019)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.3.2.137-141.2019

Objective: Report a case of thanatophoric dysplasiaMethod: Case report Result: Case of a 25-year-old woman, with a diagnosis of gravid preterm G4P2A1H2 31-32 weeks + polyhydramnios + fetal hydrops, a single intrauterine live fetus with thanatophoric dysplasia. On ultrasound examination found fetal biometry; BPD: 7.78 cm, FL: 3.58 cm, HL: 3.11 cm, AC: 30.90 cm, HC: 28.48 cm AFI: 33.27 cm, a frontal bossing (+) picture appears, claver leaf skull (+) and micromelia (proximal, distal, phalanges). The ultrasound examination suggested Severe skeletal dysplasia (thanatophoric dysplasia), polyhydramnios, + single intrauterine live fetus + SC 1x scars. Then an amnioinfusion is performed and results are obtained. Chromosome analysis is carried out using the G-banding technique. Chromosomes have been studied from 20 cells from 3 different cell culture preparations and obtained the number of chromosomes in each cell studied is 46, XY which means the number of chromosomes 46 pieces with fetal sex chromosome XY. Mosaic chromosome abnormalities generally occur due to non-disjuntion in the mitotic phase after conception. At 33-34 weeks gestation, an infant was born by SC with birth weight: 1900 g, baby’s length: 31 cm, A / S 2/3.Conclusion : Thanatophoric dysplasia is a "lethal" skeletal dysplasia. A careful prenatal examination is needed in the diagnosis and termination of pregnancy.Keywords: Thanatophoric dysplasia, prenatal diagnosis

Hydrops Fetalis Jofril Azmi; Roza Sriyanti
Andalas Obstetrics And Gynecology Journal Vol 3, No 2 (2019)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.3.2.151-155.2019

Objective: To report cases of hydrops fetalisMethod: Case reportResults: The case was a female patient aged 36 years, with a diagnosis of G3P1A1H1 gravid 23-24 weeks + Hydrops Fetalis + 1x SC former. On ultrasound examination at 23-24 weeks of age, fetal biometry was found; BPD: 58.9 mm, HC: 211.0 mm, AC: 202.5 mm, FL: 44.4 mm, HL: 40.7 mm, EFW: 417 gr, SDP: 12.79 cm, FHR: 162x / minute, shows anasarcoma edema (+), hydrothoric (+), ascites (+), impression: gravid 23-24 weeks according to biometry, live fetus, Hydrops fetalis, polyhydramnios. Then amniocentesis was carried out followed by a chromosome analysis examination carried out by the G-Banding technique. The chromosomes from 18 cells from 3 different cell culture preparations were carried out and obtained the number of chromosomes in each cell studied was 46, XY, which means that the number of chromosomes is 46. fruit with the fetal sex chromosome is XY. No major structural abnormalities were seen. At 25-26 weeks of gestation, the baby was born by SC with BBL: 2100 gr, PB: 32 cm, maceration degrees 2- 3, Hydrops Fetalis.Conclusion: Hydrops Fetalis is an abnormal accumulation of fluid in 2 or more compartments of the fetal body. The prenatal diagnosis of Hydrops Fetalis can be confirmed by fetal imaging, maternal hematology, amniocentesis.Keywords: Hydrops Fetalis, polyhydramnios

Omphalocele Revivo Rinda Pratama; Roza Sri Yanti
Andalas Obstetrics And Gynecology Journal Vol 6, No 1 (2022)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.6.1.98-103.2022

Objective: Reporting a case of omphalocele.Method: Case report.Result:Acaseofa32years-oldwoman, diagnosedwithG2P1A0H134-35weeksofpretermpregnancy+ previous Cesaran Section + omphalocele + fetal distress. According to ultrasonography, biometric measurements of the fetus were: BPD: 8.5 cm, FL: 6.4 cm, HL: 5.2 cm, AC: 27.8 cm, AFI: 23.3 cm, there were no image of abdominal wall, but a membrane surrounding the abdomen was visible. From the USG examination, the conclusion was Omphalocele.ChromosomalanalysiswasdoneusingG-Comparativetechnic,withresult46,XY,which means the amount of the chromosomes was 46, and sex chromosomes were XY. There was no major structural defect. Mostly, the disorders causing these conditions are 13, 18 and 21 trisomy, and Beckwith-WiedemannSyndrome.Conclusion: Omphalocele is a genetic disorder marked by failure of the abdominal organs to return into the abdominal cavity. It requires thorough and accurate prenatal examinations to establish a diagnosis. Keywords: Omphalocele, prenatal diagnosis

HUBUNGAN ANTARA SKIN PREPARATION DENGAN INFEKSI LUKA OPERASI POST SECTIO CAESAREA DI RS ACHMAD MOCHTAR BUKITTINGGI Calvindra Leenesa; Roza Sriyanti
Andalas Obstetrics And Gynecology Journal Vol 2, No 2 (2018)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.2.67-73.2018

Background : Surgical wound infection is a problem that is often found today in surgery. The Indonesian Ministry of Health reported that in 2011, 55.1% of surgical wound infections were found in government hospitals. This is in line with WHO data in 2010, where the sectio caesarean rate in Indonesia was recorded at 6%. Skin preparation can be used to prevent surgical wound infection by reducing the number of germs on the skin prior to incision.Objective : To see the relationship between skin preparation and post sectio caesarea surgical wound infection at Achmad Mochtar Bukittinggi Hospital.Methods : This study was an analytical study using a cross sectional study design by looking at the subject's medical records according to the time and place of the study. Samples were all medical records of mothers giving birth by sectio caesarea in the Obstetrics and Gynecology Section of Achmad Mochtar Bukittinggi Hospital in the period 1 January 2017 to 31 December 2017. Samples were taken from populations that met the inclusion and exclusion criteria. The sample was taken using simple random sampling technique which was taken from the medical records of Achmad Mochtar Hospital Bukittinggi. Statistical analysis to assess significance used the chi-square test.Results : The sectio caesarean group that carried out skin preparation without using chlorhexidine gluconate had the highest number (59.8%), with post sectio caesarean wound infection of 70.7%.Conclusion : There was a significant relationship between skin preparation and post sectio caesarean surgical wound infection (p <0.021) at Achmad Mochtar Bukittinggi Hospital.Keywords: Sectio caesarea, skin preparation, surgical wound infection

Hubungan Status Gravida, Usia, BMI (Body Mass Index) dengan Kejadian Preeklampsia Berriandi Arwan; Roza Sriyanti
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.13-21.2020

Background: Preeclampsia is one of the complications in pregnancy that can cause serious illness, long-term disability, and death in the mother, fetus and neonate. There are many risk factors that influence the occurrence of preeclampsia, such as primigravida, hyperplasentation, extreme maternal age (less than 20 years and more than 35 years), family history of preeclampsia / eclampsia, kidney disease, diabetes mellitus, chronic hypertension that has happened before pregnancy (less than 20 years and more than 35 years), family history of preeclampsia / eclampsia, kidney disease, diabetes mellitus, chronic hypertension that has been suffered before pregnancy (less than 20 years and more than 35 years). superimposed preeclampsia) and obesity. Objective: To determine the relationship between gravida status, age, and BMI status with the incidence of preeclampsia.Methods: The descriptive analytic study was using a cross sectional study design by looking at the medical records of subjects according to the time and place of research. The study population was all medical records of pregnant women with preeclampsia and those without preeclampsia in the Department of Obstetrics and Gynecology Dr. M. Djamil Padang period 1 January 2017 - 31 December 2017. Samples were taken from populations that met the inclusion criteria and did not have exclusion criteria. Sampling using consecutive sampling techniques was taken from the Medical Record Section of RSUP Dr. M. Djamil Padang. Univariate analysis was used to assess gravida status, maternal age, and BMI. Bivariate analysis was performed using the chi square test with a significance level of p <0.05.Results: A total of 63.7% of patients with severe preeclampsia were primigravida (p <0.05), 52.5% were high risk groups with age <20 years and> 35 years (p <0.05), and 55% of patients with overweight and obese group (p <0.05). Primigravida has a tendency to suffer from preeclampsia compared to multigravida. Patients who have a tendency for preeclampsia are patients with overweight and obese BMI status with a high risk age range.Conclusion: There is a significant relationship between gravida status, age, and BMI to the incidence of preeclampsia. Keywords: gravida, age, BMI, preeclampsia

Differences Post Delivery of Term Pregnancy Mean Maternal Serum Magnesium Level with Low Versus Normal Birth Weight Dovy Djanas; Heri Farnas; Roza Sriyanti; Syntia Ambelina
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 5 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i5.495

Background. Impaired fetal growth is still a major problem in obstetrics. Birth weight is usually used as an indicator of the well-being of the newborn and as an indirect measure of intrauterine nutrition during pregnancy and the mother's nutritional status during pregnancy. Magnesium contribute as a cofactor for various enzymes in the human body for metabolic processes. Fetal magnesium is obtained from maternal by transport through the placenta. In conditions of low magnesium levels will affect the epigenetic process, HPA-axis and GH-IGF axis of the fetus which in turn will result in fetal growth disorders. This study aims to determine the differences postdelivery serum magnesium levels of women at term pregnancy who give birth with low vs normal birth weight. Methods. This study used an observational analytic method with a cross sectional approach. Conducted from April 2020-December 2020 at Dr. M. Djamil Padang Central General Hospital and Network Hospital Faculty of Medicine, Andalas University. Total of 44 samples were divided into 2 groups, women who gave birth with low and normal birth weight babies. Samples was carried out at the Pramitha Padang Private Clinical Laboratory. Results: The mean maternal serum magnesium level in low birth weight group was 1.97 ± 0.16 mg/dL lower than normal birth weight group was 2.06 ± 0.14 mg/dL. Statistic test using the independent sample T test showed no differences in both groups (p = 0.064). Conclusion. The mean maternal serum magnesium level in low birth weight 1.97±0.16 mg/dL. The mean maternal serum magnesium level in normal birth weight was 2.06 ± 0.14 mg/dL. There was no significant difference on both groups.

Relationship of Ferritin Levels of Pregnant Women Who Had Fe Deficiency Anemia with Ferritin Levels and APGAR of the Neonates Zuliyana Zuliyana; Yanwirasti Yanwirasti; Roza Sri Yanti
Journal of Midwifery Vol 3, No 2 (2018): Published on December 2018
Publisher : Universitas Andalas

Iron deficiency anemia in pregnant women can have a negative impact on the baby, such as placental development, low birth weight, prematurity, baby health, hypoxia, decreased immune status, possibility of having physiological disorders and infant growth. The aim of this study was to determine the relationship of ferritin levels of pregnant women who had Fe deficiency anemia with ferritin levels and Apgarof the neonates.This was a cross sectional study in the population of pregnant women who had Fe deficiency anemia and neonates who met the inclusion criteria taken by consecutive sampling technique in the working area of Lubuk Buaya Health Center, Ambacang Health Center and Ikur Koto Health Center. Examination of ferritin levels was carried out in the Biomedical Laboratory of Faculty of Medicine, Andalas University using ELISA method. Data were analyzed by Pearson Test and Mann-Whitney Test. The results of this study showed there was no significant relationship between maternal ferritin levels on neonatal ferritin r = 0.248, p = 0.204. It also showed that there was no relationship between maternal ferritin levels on APGAR p value = 0.199 and there was a significant relationship between neonatal ferritin levels on APGAR p value = 0.002. The conclusion of this study is that there was a positive relationship between maternal ferritin levels with neonatal ferritin levels, there was no significant relationship between maternal ferritin levels and APGAR score, there is a significant relationship betweenneonatal ferritin levels with APGAR score. By improving nutrition, socioeconomic, qualitative antenatal care, early referral of risky cases and iron supplementation can reduce the incidence of anemia.

Karakteristik Pasien Bersalin dengan HIV Positif dan Tingkat Keberhasilan Pemberian ARV Profilaksis pada Bayi Baru Lahir Syntia Ambelina; Roza Sri Yanti
Indonesian Journal of Obstetrics & Gynecology Science Volume 2 Nomor 2 September 2019
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Tujuan: Mengetahui karakteristik pasien bersalin dengan HIV positif dan pencapaian pemberian anti retro viral (ARV) profilaksis pada bayi baru lahir di RSUP M. Djamil Padang.Metode: Penelitian ini merupakan studi deskriptif menggunakan desain cross sectional study. Penelitian dilakukan di bagian kebidanan RSUP M. Djamil Padang periode 1 Januari 2017−31 Desember 2018 dengan melakukan penelusuran rekam medis pasien obstetri HIV positif. Sampel penilitian ini adalah seluruh pasien dengan HIV positif yang bersalin dalam rentang periode 1 Januari 2017−31 Desember 2018.Hasil: Selama periode penelitian didapatkan total 1068 pasien bersalin di RSUP M. Djamil Padang. Didapatkan dua puluh sampel dengan HIV positif, dimana 5 sampel (25%) merupakan pasien yang berasal dari rujukan Puskesmas di Kota Padang, dan sisanya dari rujukan berbagai rumah sakit kabupaten di Sumatera Barat. Mayoritas sampel berusia 20-35 tahun (85%), pendidikan SMA (40%), menikah satu kali (60%), multigravida 2-4 (80%), dan dilakukan terminasi kehamilan pada usia kehamilan 37−42 minggu (100%). 85% sampel merupakan pasien dengan status HIV yang telah dikenal dan mendapat terapi ARV sebelumnya. 5% sampel bersalin secara spontan dan 95% sampel bersalin secara seksio sesarea. Seluruh bayi baru lahir dari ibu dengan HIV positif mendapatkan ARV profilaksis pada empat jam pertama pasca persalinan.Kesimpulan: Prevalensi persalinan dengan HIV positif di RSUP M. Djamil Padang adalah 1,87%, dan pencapaian pemberian ARV profilaksis pada bayi baru lahir adalah 100%. Characteristics of Maternity Patients with HIV Positive and Achieving Provision of ARV Prophylaxis in NewbornsAbstractObjective: To determine the characteristics of HIV positive maternity patients and the achievement of prophylactic anti retro viral (ARV) provision in newborns at M. Djamil Hospital Padang.Method: This is a descriptive study using a cross sectional study design. The study was conducted in department of M. Djamil Hospital Padang period January 1st, 2017−December 31st, 2018 through the search of medical records of HIV positive obstetric patients. This research sample is all HIV positive patients who deliver within period January 1st, 2017-December 31st, 2018.Result: There were 1068 patients gave birth during the study period. Twenty samples were found to be HIV positive, of which 5 samples (25%) patients came from referrals of primary health care in Padang, and the remainder were referrals from various district hospitals in West Sumatra. The majority of the sample were 20−35 years of age (85%), high school education (40%), married once (60%), multigravida 2−4 (80%), and termination of pregnancy at 37-42 weeks of gestation (100%). 85% of the samples were patients with known HIV status and were previously treated with ARVs. 5% of spontaneous maternity samples and 95% of samples delivered by cesarean section. All newborns from HIV-positive mothers get prophylactic ARVs in the first four hours postpartum.Conclusion: The prevalence of HIV positive labor in M. Djamil Hospital Padang is 1.87%, and the achievement of prophylactic ARV administration at newborns is 100%.Key words: HIV Positive, ARVs, Pregnant Women, Newborn

Co-Authors Berriandi Arwan Calvindra Leenesa Dovy Djanas Hafni Bachtiar Heri Farnas Heri Farnas Ilmiawati, Ilmiawati Jofril Azmi Johanes C. Mose Masrul Masrul Netti Suharti Rengga Pradipta Rengga Pradipta Revivo Rinda Pratama Syntia Ambelina Syntia Ambelina Tria Sari Retno Asih Violita Dianatha Puteri Yanwirasti Yanwirasti Zuliyana Zuliyana

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