Alpinia purpurata (Vieill.) K.Schum contains flavonoids, tannins, saponins, and terpenoids which have bacterial inhibitory power. This study aims to determine the antibacterial activity test of ethanol extract 96% Alpinia purpurata (Vieill.) K.Schum on the growth inhibition power of Staphylococcus aureus. This research is an experimental research. Antibacterial activity test of extract ethanol 96% Alpinia purpurata (Vieill.) K.Schum using Cup Plate Technique with concentrations of 40%, 30%, 20%, 10% and 5%, Clindamycin concentration 50μg/ml as control (+) and 96% ethanol as control (-) in each treatment replication 4 times. The results diameter of the inhibitory zone formed was then analyzed by Statistical Producy Service Solution (SPSS) version 17. The results showed that extract ethanol 96% of Alpinia purpurata (Vieill.) K.Schum had inhibitory activity on the growth of Staphylococcus aureus. The average diameter of the extract ethanol 96% inhibition zone of Alpinia purpurata (Vieill.) K.Schum with a concentration of 40%, 30%, 20%, 10% and 5%, positive control (clindamycin), and negative control (96% ethanol) respectively on Staphylococcus aureus bacteria is 28.06 mm; 25.17 mm; 23.15 mm; 20.38 mm; 18.34 mm; 30.13 mm; 0 mm. There are significant differences in diameter of inhibitory zones between concentrations of extract ethanol 96% of Alpinia purpurata (Vieill.) K.Schum on the growth of Staphylococcus aureus bacteria with significance values 0,000.
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