Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Vol 6 No 2 (2021): JIIS

FORMULASI, KARAKTERISASI DAN UJI STABILITAS MIKROEMULSI MINYAK NILAM (Pogostemon cablin Benth.)

Benni Iskandar (Unknown)
Anita Lukman (Unknown)
Raesa Tartilla (Unknown)
Meircurius Dwi Condro Surboyo (Unknown)
Leny Leny (Unknown)



Article Info

Publish Date
25 Oct 2021

Abstract

Patchouli oil contains patchouli alcohol as the main component which is a tricyclic tertiary alcohol sesquiterpene compound that is insoluble in water. Microemulsion is a droplet dispersion technology that combines an insoluble liquid with another liquid. The role of surfactants in helping the dispersion process of microemulsion formulation is by reducing the interfacial tension. Microemulsion is a supersolvents carrier, so that both hydrophilic and lipophilic can be administered through a microemulsion system. The purpose of this study was to formulate patchouli oil into a stable microemulsion preparation. This research was conducted by making 4 preparations of patchouli oil microemulsion containing 5% (F1), 10% (F2), and 15% (F3) patchouli oil, and microemulsion without patchouli oil (F0). Evaluation of microemulsion preparations includes organoleptic test, pH measurement, density determination, viscosity test, freeze and thaw test, centrifugation test, and particle size analysis. The test results showed that the microemulsion containing 5% patchouli oil had the most stable characteristics compared to other formulas.

Copyrights © 2021






Journal Info

Abbrev

JIIS

Publisher

Subject

Medicine & Pharmacology

Description

Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIIS is a forum for the publication of quality and original works ...