Journal Syifa Sciences and Clinical Research (JSSCR)
Vol 2, No 2 (2020): Volume 2 Edisi 2 2020

Formulasi Sediaan Masker Gel Peel-Off dari Ekstrak Buah Tomat (Solanum Lycopersicum L.) Beserta Uji Aktivitas Antioksidan

Wa Ode Sitti Zubaydah (Jurusan Farmasi, Fakultas Farmasi, Universitas Halu Oleo, Jl. HEA Mokodompit, Kampus Hijau Bumi Tridharma Anduonohu Kendari 93232, Indonesia)
Selly Septi Fandinata (Farmasi, Akademi Farmasi Surabaya, Jl. Ketintang Madya No. 81 Kota Surabaya 60231, Indonesia)



Article Info

Publish Date
02 Sep 2020

Abstract

Tomatoes are well-known as the source of antioxidants due to the content of lycopene, i.e., a potential free radical inhibitor. Gel peel-off masks are among the chemical products containing antioxidants. The first step of the study was extracting tomato fruits by macerating the fruits using alcohol solvents 96%. The obtained thick extract was used as the material of the gel mask; the percentage of the extract comprised 3% (F1), 5% (F2), and 7% (F3), and it used PVA basis 11% and viscolam 3%. According to the result, the gel peel-off masks meet the requirements of physical and storage stability evaluation. The result of the antioxidant test reveals that the IC50 value of the three masks is F1 189.22 µg/mL, F2 89.34 µg/mL, and F3 36.77 µg/mL. Further, the result of T-Test reveals that P-value = 0.019 (α = 0.05), indicating a difference in the result of the antioxidant test of the three formulae in day one (t0) and day 28 (t28).

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Journal Info

Abbrev

jsscr

Publisher

Subject

Chemistry Medicine & Pharmacology

Description

Journal Syifa Sciences & Clinical Research (JSSCR) is a national journal intended as a communication forum for scientists from many practitioners who use Pharmacology Development in ...