Nusantara Medical Science Journal
Volume 7 Issue 1, January - June 2022

Survivability Rates Based on Molecular Subtype, Stage and Metastasis of 36 months cohort in Breast Cancer Patients

Adi Wijayanto (a:1:{s:5:"en_US"
s:22:"Universitas Hasanuddin"
})

John S. L. A. Pieter (Department of Surgery, Subdivision of Oncology, Faculty of Medicine,Universitas Hasanuddin)
Prihantono (Department of Surgery, Subdivision of Oncology, Faculty of Medicine,Universitas Hasanuddin)
Salman Ardy Syamsu (Department of Surgery, Subdivision of Oncology, Faculty of Medicine,Universitas Hasanuddin)
Nilam Smaradhania Thaufix (Department of Surgery, Subdivision of Oncology, Faculty of Medicine,Universitas Hasanuddin)
Amirullah Abdi (Faculty of Medicine, Universitas Hasanuddin)



Article Info

Publish Date
16 Apr 2022

Abstract

Introduction:  Breast cancer treatment is carried out at the early stage of the disease, and a comprehensive assessment of the subtype, stage, and incidence of metastases is required. This study aims to determine breast cancer patients' overall survival (OS) and disease-free survival (DFS) based on subtype, stage, and incidence of metastases. Methods:  An observational analytic study with a retrospective cohort design was performed on eligible breast cancer patients at Wahidin Sudirohusodo Hospital from 2016 to 2019. Univariate analysis, and the Kaplan-Meier survival log-rank method (Mantel-Cox), were used to determine differences in survivability rates (OS and DFS) based on subtype, stage, and incidence of metastases. Results:   A total of 172 breast cancer patients from 32 years to 84 years with a mean age of 53.5 years. The most subtypes were Luminal A (34.9%) patients, and the least was Luminal B (15.7%) patients. A total of 85 (49.4%) patients survived during these three years, while 87 (50.6%) died. Based on the results of statistical tests in this study, there were no significant differences between the subtypes with DFS and OS, but on the contrary, there was a significant difference between the stage and incidence of metastases with OS and DFS (p<0.05). Conclusions:  There were no statistically significant differences between the subtypes with OS and DFS. This study showed a significant difference between the stage and incidence of metastases with OS and DFS

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Journal Info

Abbrev

jmednus

Publisher

Subject

Materials Science & Nanotechnology Neuroscience

Description

Nusantara Medical Science Journal (NMSJ) is an open access, peer-reviewed journal published by Faculty of Medicine, Hasanuddin University twice a year in June and December. NMSJ encompasses all basic and molecular aspects of medical sciences, with an emphasis on the molecular studies of biomedical ...