The research in this paper aims to determine the effectiveness of immunostimulants from ethanol extract of coffee parasite leaves (Loranthus ferrugineus Roxb) with four variants of doses of 50mg / kgBB, 100mg / kgBB, 200mg / kgBB, 400mg / kgBB. This study used 18 male white rats with 200 gram BB which were divided into 6 treatment groups. Rats were injected with 0.1ml SDMS 1% for 7 consecutive days intraperitoneal, then on the 7th day each blood sample was taken through veins in the tail, CMC Na 0.5% suspension, and Levamisole suspension 50mg / kgBB as a positive control was administered orally on the 8th day. Then blood samples were collected in a micro tube and then 1900rpm was centrifuged at a temperature of 4oC for 10 minutes. The results of the study of ethanol extract of coffee parasite leaves proved effective as immunostimulants because they have a value close to positive control, starting from a dose of 200mg / kgBB to 400mg / kgBB.
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