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PENGARUH EKSTRAK UMBI BAWANG PUTIH DAN UMBI BAWANG MERAH TERHADAP LUKA BAKAR PADA KELINCI Bunga Rimta Barus; Indah Lestari
Jurnal FARMASIMED (JFM) Vol 1 No 1 (2018): Jurnal FARMASIMED (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Burns are one of the most common types of injuries in the community. The content of alliin in garlic (Allium sativum L) and onion (Allium cepavarascalonicum) is believed to help heal burns, with its biological activity as anti-aggregation of platelet cells, boost fibrinolysis and as an anti-bacterial. Objective of this research is to know the effect of gaelic extract (Allium sativum L) and red onion (Allium cepa var ascalonicum) to burn on rabbit.The methodology of this research is an experimental method based on a complete randomized design.sample used in this research and onion bulbs taken in Berastagi Subdistrict, Karo Regency, North Sumatera Province.Result of this research show that subjects of Garlic extract with 15% concentration gave the fastest healing effect on 7th day, 10% and 5% dose gave healing effect on the 8th day. Giving onion bulbs extract at 15%, 10% and 5% concentration gave healing effect of burn on 8th day. The healing of burns in the comparison group was on the 8th day while the longest burn healing in the control group was on the 10th day. Conclusion is an effect that can be found in the extract of garlic and onion extract to the burn on the rabbit.

Formulasi Sediaan Pengharum Ruangan Dari Minyak Melati Dengan Minyak Akar Wangi Sebagai Pengikat Christica Illsanna Surbakti; Eka Swadana
Jurnal FARMASIMED (JFM) Vol 1 No 1 (2018): Jurnal FARMASIMED (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Fragrance is a growing product today, one of which is in the form of air freshener. Fragrance materials used in the product are divided into two types, namely synthetic deodorizer and natural fragrance. Synthetic deodorizer has a sharper fragrance, so it can cause dizziness, while natural fragrance has a softer fragrance.The selection of gel form is because it is more durable and practical in use. Purpose: The purpose of this study for formulate carrageenan and natrium alginat as a base of gel air freshener, for formulate jasmine oil with the various concentration as a fragrance, for formulate vetiver oil with the various concentration as a fixative Methods: This research consist of three stages. First, looking for the best base of gel air freshener by using combination of carrageenan and natrium alginat with three percent concentration at many comparison, they are 70:30, 60:40, 40:60, 30:70. And then, looking for the best fragrance by using rose oil at many concentration. They are 1%, 2%, 4% dan 6%. And then, looking for the best concentration of vetiver oil that can endurance the fragrance of jasmine oil for the longest time on storage in different place, such as AC room and fan room. Results: The results of this study indicate that the best gel formulation are mixture carrageenan and natrium alginat with comparison 70:30. The best fragrance of jasmine oil is eight percent concentration. The longest fragrance endurance is vetiver oil with one percent concentration. Conclusion: Combination of carrageenan and natrium alginat with comparison 70:30 can be formulated as a base of gel air freshener, the best concentration of jasmine oil is four percent, and the best concentration of vetiver oil is one percent

Penetapan Kadar Na-Siklamat Pada Minuman Serbuk Instan Dan Minuman Kemasan Kaleng Yang Diperdagangkan Di Delitua Dengan Metode Alkalimetri Parhan Parhan
Jurnal FARMASIMED (JFM) Vol 1 No 1 (2018): Jurnal FARMASIMED (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Packaging beverages or soft drinks are non-alcoholic beverages, processed or powdered liquors containing foodstuffs or other additives both natural and synthetic packaged in ready-to-eat packaging. Instant powder drink is one of the fast food beverage products that contain many artificial sweeteners. The most commonly used artificial sweetener is Na-cyclamate. The use of Na-Cyclamate in large doses will cause health problems. The purpose of this research is to know and compare the content of Na-Cyclamate in instant powder drink with beverage of canned packaging traded in Delitua with provisions SNI 01-6993-2004 that is 1000 mg / kg BB. Samples were collected from drink merchants in Delitua who sold instant powder beverages according to qualitative qualitative analysis criteria that aimed to see the Na-Cyclamate content in the sample by using the sedimentation test with BaCl2. Positive samples containing Na-Cyclamate were determined by Alkalimetry. The results showed that 6 samples of instant powdered beverage and canned container beverage contained Na-Cyclamate with content: A (402,2629 mg / kg), B (395.9280 mg / kg), C (405,4303 mg / kg ), D (272.3985 mg / kg), E (269.2311 mg / kg), and F (392.7606 mg / kg). From the data obtained, it is known that the samples A, B, C, D, E and F are safe for consumption, since the Na-Cyclamate content of the sample does not exceed the limits set by SNI 01-6993-2004 based on the food category of 1000 mg / kg. Na-Cyclamate content found in instant powder drink is higher than Na-Cyclamate levels contained in beverage cans packaging.

UJI AKTIVITAS KANDUNGAN ANTIOKSIDAN PADA DAUN BANGUN-BANGUN (PLECTRANTHUS AMBOINICUS) SECARA SPEKTROFOTOMETRI ULTRAVIOLET-VISIBLE Vera Estefania Kaban; Siti Yusmarlisa
Jurnal FARMASIMED (JFM) Vol 1 No 1 (2018): Jurnal FARMASIMED (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

The population explosion that occurred in Indonesia has a profound effect on the quality of life of the community, such as the decline in the level of public health. Therefore leaf plants can be used as medicines that can be useful as antioxidants. Antioxidants are compounds that can inhibit free radicals due to the presence of reactive oxygen, so as to prevent various degenerative diseases. The compounds in the leaves of the buildings include flavonoids, alkaloids and polyphenols. To determine the presence of antioxidant content in wake-up leaves and to determine differences in antioxidant concentrations in wake-up leaves with vitamin C. Samples of leaves of the buildings used were obtained from the Pematang Siantar area, North Sumatra. Sample preparation was carried out by making leaf extracts. The activity test of antioxidant content in the wake-up leaf extract using ultraviolet-visible spectrophotometry. The results showed that there was a decrease in the value of DPPH absorbance given by the wake-up leaf extract test sample with vitamin C. A decrease in the absorbance value indicates a greater DPPH damping activity. The highest DPPH damping activity by leaf extracts of buildings with IC50 values of 20,2842 ppm can be categorized as having very strong DPPH damping activity. There is an antioxidant content with the IC50 category which is very strong in the leaves of the wake-up plant (Plectranthus amboinicus) and the higher the concentration of a test sample of wake-up leaf extract (Plectranthus amboinicus) and BPFI of vitamin C, the absorbance value decreases, The percentage of damping is higher and IC50 is lower, the antioxidant activity is higher.

SEDIAAN SALEP EKSTRAK DAUN KELOR (MORINGA OLEIFERA LAM) SEBAGAI PENYEMBUHAN LUKA BAKAR TOPIKAL PADA KELINCI (ORYCTOLAGUS CUNICULUS) Wahyudi Wahyudi; Hanna Agustina
Jurnal FARMASIMED (JFM) Vol 1 No 1 (2018): Jurnal FARMASIMED (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Burns is a form of tissue damage caused by contact with a heat source such as fire, hot water, chemicals, electricity and radiation. Burns occur on the skin, mucous membranes, respiratory tract and gastrointestinal tract. Actions that can be performed on burns is to provide local treatment with the aim to get relief as quickly as possible. One of the traditional medicines used empirically society as burn treatment is by softening Moringa leaves Moringa leaves and placed on the affected part of the wound. This tudy aim to determine the effect of healing of burns using Moringa leaf extract ointment and to determine the concentration of Moringa leaf extract in the ointment preparation is most effective in the healing of burns. Experimental method. Result of this study show phytochemical screening results indicate the presence of alkaloids, flavonoids, saponins, tannins. observations of Moringa leaf extract ointment preparation during storage of 7 days showed that the formula has a good appearance, homogeneous, smell and color. Diameter burns decline, a group of rabbits treated with the ointment extract of the leaves of Moringa 6% that is 0.9 cm, a group of rabbits given ointment extract of the leaves of Moringa 8% ie 0.91 cm, a group of rabbits given ointment extract of Moringa leaves 10% that is 0.95 cm, BioplacentonÂ® namely the group given 0.89 cm, while the group of rabbits given distilled water of 0.77 cm. Conclusion of this study show that extracts leaves of Moringa had an effect in the healing of burns. Ointments Moringa leaf extract 10% of the most effective in the healing of burns and has a greater potential than the BioplacentonÂ®. Burn healing effect on the concentration of 8% and 6% more effective than the negative comparison.

Uji Mutu Ekstrak Daun Sirsak (Annona muricata Linn.) Yang Di Ekstraksi Secara Maserasi Dengan Pelarut Etanol 70% Christica ilsannas surbakti; Nadiya Nadiya Nadiya
Jurnal FARMASIMED (JFM) Vol 1 No 2 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Background : Gastric ulcer is wound to the mucosal layer (epithelial layer) of the stomach and mucosal irritation of 5 mm or more in diameter with depth down to submucosa. The basic pathogenesis of gastric ulcers in when there is an imbalance of aggressive factor enhancement. Non-steroidal antiinflammantory drug can cause stomach ulcers in two ways, either directly or topical irritation of the epithelial tissue and inhibit the endogeneous system of gastrointestinal mucosa of prostaglandins. In this case inhibition of prostaglandin systhesis is the dominant factor of peptic ulcers by NSAIDs. Objectives : The purpose of this study was to determine the effct of NSAID drug administration on the formation of peptic ulcers and to know the difference in the rate of formation of peptic ulcers from each class. Method : Sampel method mice performed surgery on the stomach is done in Pharmacology Laboratory of Pharmacy Institute Deli Husada Deli Tua. Results : The results of this study indicate that faster drugs cause gastric ulcers with a degree of redness are Aspirin 4.03 mm, 2.01 mm mefenamat and 1.02 mm Diclofenac Sodium while Ibuprofen mwdication does not cause peptic ulcers. Conclusion : The results of this study it can be concluded that Aspirin administration with doses of 21 mg/kg faster causes gastric ulcers from other NSAID groups such as Mefenamat with a dose of 21 mg/kg BW, Diclofenac sodium at a dose of 2 mg/kg while administration, Ibuprofen for ten days does not couse ulcers in the stomach of experimetal animals.

Formulasi Pembuatan Sediaan Eyeshadow dari Ekstrak Bunga Kecombrang (Etlingera elatior Jack) Bunga Rimta Barus; Vera Estefania Kaban
Jurnal FARMASIMED (JFM) Vol 1 No 2 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

One type of cosmetic or decorative cosmetic preparation is eyeshadow which contains a color pigment applied to the eyelid. The purpose of this study was to find out that kecombrang flower extract can be used as eyelid coloring. From the study to make eyeshadow preparations using dyes extracted from kecombrang flowers, to determine the stability of the eyeshadow by using kecombrang flower extract in storage at room temperature, and to find out whether eyeshadow preparations using extracts from kecombrang flowers cause irritation when used. Eyeshadow preparations from kecombrang flower extract (Etlingera elatior Jack) were made in various concentrations of 15%, 17.5%, 20%, 22.5%, 25% and blank preparations (without using kecombrang flower extract). Physical quality inspection of the preparation includes: color dispersion test (homogeneity), cracking test, and stock stability test. And for other tests carried out polishing tests (homogeneity) and irritation tests. Eyeshadow from kecombrang flower extract also does not cause irritation and is stable in room temperature storage for 30 days. Preparation of kecombrang flower extract with several good concentrations was used as eyeshadow preparations, stable eyeshadow preparations in storage at room temperature within 30 days, and the formulation of eyeshadow preparations using kecombrang flower extract as eyelid coloring did not cause irritation.

Pengaruh Kecepatan Pembentukan Tukak Lambung Terhadap Pemberian Berbagai Golongan NSAID Pada Tikus Jantan Parhan Parhan; Aliman Yafarugi Gulo
Jurnal FARMASIMED (JFM) Vol 1 No 2 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Background : Gastric ulcer is wound to the mucosal layer (epithelial layer) of the stomach and mucosal irritation of 5 mm or more in diameter with depth down to submucosa. The basic pathogenesis of gastric ulcers in when there is an imbalance of aggressive factor enhancement. Non-steroidal antiinflammantory drug can cause stomach ulcers in two ways, either directly or topical irritation of the epithelial tissue and inhibit the endogeneous system of gastrointestinal mucosa of prostaglandins. In this case inhibition of prostaglandin systhesis is the dominant factor of peptic ulcers by NSAIDs. Objectives : The purpose of this study was to determine the effct of NSAID drug administration on the formation of peptic ulcers and to know the difference in the rate of formation of peptic ulcers from each class. Method : Sampel method mice performed surgery on the stomach is done in Pharmacology Laboratory of Pharmacy Institute Deli Husada Deli Tua. Results : The results of this study indicate that faster drugs cause gastric ulcers with a degree of redness are Aspirin 4.03 mm, 2.01 mm mefenamat and 1.02 mm Diclofenac Sodium while Ibuprofen mwdication does not cause peptic ulcers. Conclusion : The results of this study it can be concluded that Aspirin administration with doses of 21 mg/kg faster causes gastric ulcers from other NSAID groups such as Mefenamat with a dose of 21 mg/kg BW, Diclofenac sodium at a dose of 2 mg/kg while administration, Ibuprofen for ten days does not couse ulcers in the stomach of experimetal animals.

Efektifitas Lumatan Daun Jambu Biji (Psidium guajava linn) Terhadap Penyembuhan Luka Bakar (Vulnus combustion) Pada Kelinci Wahyudi Wahyudi Wahyudi; Dian Ika Perbina
Jurnal FARMASIMED (JFM) Vol 1 No 2 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Guava (Guava guajava linn) or guava contains high pectin so it can lower cholesterol, contain tannins that serves to improve the digestive system. Chemical compounds contained in the fruit guava echoes its shape is quersetin i.e. the type of flavonoid compounds a flavonol, flavones, and flavol, which helps them were to treat the fragility of capillaries in the human. The purpose of this research is to know the effectiveness of guava leaf lumatan (Guava guajava linn) in burn healing in rabbits. The methods used in this study was an experimental method using a control group, the Group and the comparison group test (perlakuaan). The results showed that of the negative control group provides the longest healing impact i.e. on the 13th, the positive control healing burns on day 8, and control using lumatan guava leaf healing burns on day 9 control group comparison, bioplacenton indicates days of healing Burns most rapidly healed.

Perbedaan Teknik Penanaman Terhadap Hasil Jumlah Koloni Bakteri Escherichia Coli Pada Suhu Inkubasi 36C VINCENTIA ADE RIZKY
Jurnal FARMASIMED (JFM) Vol 1 No 2 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Escherichia coli bacteria are gram-negative bacteria in form of single or paired cells it is included Enterobacteriaceae family and intestinal normal flora. Laboratory tests conducted for the calculation of the number of germs can be done using cultivation techniques using a loop and micropipet. The aim of this research is to know the difference of number of bacteria bacteria on calibrated loop and micropipet to colony of Escherichia coli bacteria. This research is an analytical observation study with cross sectional design. The hypothesis was tested using independent t test with 95% confidence level. The results showed the average number colonies of Escherichia coli bacteria growing on PCA media using calibrated loop technique was 138,25 CFU/mL where as the average number of colonies of Escherichia coli bacteria grown on PCA media using micropipet technique was 104,56 CFU/mL, and significant value of p = 0,001. Furthemore, the result of data analysis showed that there were no any differences in the number of colonies of Escherichia coli bacteria in planting using calibrated loop technique and micropipet at incubation temperature of 36ÂºC.

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Beny Irawan

Contact Email benyirawan77@gmail.com

Phone -

Journal Mail Official benyirawan77@gmail.com

Editorial Address -

Location Kab. deli serdang, Sumatera utara INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Beny Irawan

Contact Email
benyirawan77@gmail.com

Phone
-

Journal Mail Official
benyirawan77@gmail.com

Editorial Address
-

Location
Kab. deli serdang,

Sumatera utara

INDONESIA