Biomolecular and Health Science Journal
Vol. 5 No. 1 (2022): Biomolecular and Health Science Journal

Diathesis Hemorrhagic, Coagulation and Fibrinolytic System

Rizky Amalia Putri (Unknown)
Muhammad Noor Diansyah (Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia)
Ami Ashariati Ashariati (Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia)
Siprianus Ugroseno Yudho Bintoro (Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia)
Putu Niken Ayu Amrita (Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia)
Merlyna Savitri Savitri (Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia)
Pradana Zaky Romadhon (Medical Hematology Oncology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital Surabaya, Indonesia)



Article Info

Publish Date
28 Apr 2022

Abstract

Bleeding is one of the most common complaints when coming to the hospital which can be mild to life-threatening. The balance of the impaired hemostasis system allows for abnormal bleeding such as hemorrhagic diathesis. Balance between blood clotting and bleeding is always maintained in the body under normal physiology. The coagulation system stops existing bleeding with vasoconstricts of blood vessels and the formation of early platelet plugs, this blockage is strengthened by the presence of a cascade of coagulations to form stable and sturdy blockages. Once bleeding has stopped, the fibrinolytic pathway is initiated to dissolve the blood clot to restore normal blood flow. balance the coagulants, fibrinolytic and inhibitor systems, creating a perfect physiological balance. Hemostatic imbalance is a global problem that can lead to thrombosis or hemorrhage.

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Journal Info

Abbrev

BHSJ

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Description

Bimolecular and Health Science Journal (BHSJ) is a scientific peer-reviewed medical doctor which relevant to a medical doctor and other health-related professions by the Faculty of Medicine Universitas Airlangga, Indonesia. BHSJ provides a forum for original article, review article, editorial, case ...