Jurnal Kesehatan Gigi
Vol 8, No 1: Juni 2021

Efek gel ekstrak daun kemangi (Ocimum sanctum l.) terhadap luas ulkus traumatikus pada Rattus norvegicus

Nikmatus Sa'adah (Institut Ilmu Kesehatan Bhakti Wiyata Kediri)
Hening Tuti Hendarti (Institut Ilmu Kesehatan Bhakti Wiyata Kediri)
Herlambang Prehananto (Institut Ilmu Kesehatan Bhakti Wiyata)
Bagus Soebadi (Institut Ilmu Kesehatan Bhakti Wiyata Kediri)
Eka Putri Pertiwi (Institut Ilmu Kesehatan Bhakti Wiyata Kediri)
Agus Aan Adriansyah (Universitas Nahdlatul Ulama Surabaya)



Article Info

Publish Date
23 Jun 2021

Abstract

Introduction: Traumatic ulcers are damage to the mucosal tissue of the oral cavity which causes some of the epithelial structures to be lost to exceed the basement membrane or even reach the lamina propia. The causes of ulcers is trauma, which can be physical, mechanical, thermal or chemical trauma. One of traditional treatments for traumatic ulcers is basil (Ocimum sanctum L.) leaves which contain such as alkaloids, saponins, flavonoids, and tannins as anti-inflammatory. This research was aimed to prove the effect of basil leaves (Ocimum sanctum L.) extract gel with a concentration of 0.5%, 1%, and 1.5% to traumatic ulcer area in Rattus norvegicus. Method: Laboratory experimental study with a post test only control group design. The basil leaves extract made into a gel concentration of 0.5%, 1, and 1.5%, and the control group using a CMC-Na gel, applied to Rattus norvegicus which had been made before by a traumatic ulcer. Traumatic ulcer area measurements using digital calipers on day 0, day 3, day 5, and day 7. The data were analyzed by oneway ANOVA test. Results: The significance value on one way anova test of research group was 0,000. Average traumatic ulcer area in research group smaller than control group. Conclusion: There was an effect of basil leaves (Ocimum sanctum L.) extract gel to traumatic ulcer area in Rattus norvegicus.

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Journal Info

Abbrev

jkg

Publisher

Subject

Dentistry

Description

Jurnal Kesehatan Gigi includes an article on dental health research (p-ISSN: 2407-0866 e-ISSN: 2621-3664) Jurnal Kesehatan Gigi is a journal publish original research papers, review articles and case studies focused on : Dental nursing, dental health, dentistry, community dental health, dental and ...