Jurnal Sains dan Kesehatan
Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)

Aktivitas Antiulseratif Berbagai Tanaman Herbal dan Prospek Masa Depan Sebagai Tanaman Budidaya : Anti-ulceritis Activity of Various Herbal Plants and Future Prospects as Cultivated Plants

Hafizh Zahra (IPB University)
Rosa Berlina Haridas (IPB University)
Gusnia Meilin Gholam (IPB University)
Aprijal Ghiyas Setiawan (IPB University)



Article Info

Publish Date
30 Jun 2022

Abstract

Peptic ulcer disease (PUD) is one of the most common gastrointestinal disorders in individuals aged 20-50 with 1081 cases of death (0.08%) in Indonesia. The main risk factors for PUD include the use of non-steroidal anti-inflammatory drugs, Helicobacter pylori infection, alcohol, smoking, and physical stress. Nowadays, PUD treatment has transformed using secondary metabolites of herbal plants to compete with allopathic treatment adverse effects. Through this systemic review, several herbal plant metabolites from various studies are responsible for gastroprotective, inhibition of certain neurotransmitters, proton pump repression, or different anti-inflammatory effects. The literature search was carried through extensive databases (PubMed, Science Direct, Semantic Scholar, Springer Link, SAGE, and Google Scholar) with keywords linked with PUD. The scope of the data investigated included plant species, groups of metabolites, in vivo application doses, metabolites mechanism of action, and analytical methods.

Copyrights © 2022






Journal Info

Abbrev

jsk

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

Description

Jurnal Sains dan Kesehatan (J. Sains. Kes) (e-ISSN 2407-6082, p-ISSN 2303-0267), is a national journal with ISSN and published four times a year in 2015. In 2016 the publishing frequency changed to twice a year. In 2021 the frequency increased to six times a year. Jurnal Sains dan Kesehatan is ...