Media Farmasi Indonesia
Vol. 13 No. 2 (2018): Media Farmasi Indonesia

THE EFFECTIVENESS OF SOLVENT PROPORTIONS ON ANTIOXIDANT PROPERTIES OF WANGON (Olax psittacorum (Wild.) Vahl.) LEAVES

Reslely Harjanti (Unknown)
Siti Aisiyah (Unknown)
Vivin Nopiyanti (Unknown)



Article Info

Publish Date
01 Oct 2018

Abstract

The aim of this research was to find out the proportion of food grade and effective ethanol solvent to extract antioxidant phytoconstituents in wangon leaves. This study used 50%, 70% and 96% ethanol solvent. Wangon leaves were extracted with soxhlet method to produce the corresponding extract. Then the extract was tested for its antioxidant activity and the levels of the compound suspected to be active as an antioxidant compound including flavonoids and phenolic total were determined. The results showed that the best solvent proportion for extracting wangon leaves to have the greatest antioxidant activity was 96% ethanol. It was proved that 96% ethanol extract has potency as antioxidant with IC50 value equal to 71,27 ppm better than 50% and 70% ethanol extract. The 96% ethanol extract also had the greatest flavonoid and phenolic content of 99.44 ± 1.27mg Quercelia equivalent (QE)/g samples and 121.66 ± 1.39 mg Gallic acid equivalent (GAE)/g samples. The content of flavonoid and phenolic phytoconstituents in the extract has a linear correlation and was strongly associated with its antioxidant activity.

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Journal Info

Abbrev

MFI

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Other

Description

Media Farmasi Indonesia publishes original article in the all scopes of Pharmaceutical Science such as Pharmaceutics, Biopharmaceutics, Drug Delivery System, Chemical Pharmacy, Pharmaceutical Technology, Pharmaceutical Microbiology and Biotechnology, Pharmacology and Toxicology, Pharmacokinetics, ...