Pharmaceutical Sciences and Research (PSR)


Challenge and Development Strategy for Colon-Targeted Drug Delivery System

Iswandana, Raditya (Unknown)
Putri, Kurnia Sari Setio (Unknown)
Putri, Fathia Amalia (Unknown)
Gunawan, Maxius (Unknown)
Larasati, Sekar Arum (Unknown)



Article Info

Publish Date
30 Apr 2022

Abstract

Colon-Targeted Drug Delivery System (CTDDS) is able to improve local therapeutic effects in the treatment of colon-specific diseases, such as Crohn’s disease, Ulcerative Colitis (UC), and Irritable Bowel Syndrome (IBS). A colon can also be a suitable site for systemic delivery of drugs susceptible to extreme gastric pH, such as peptides and protein therapeutics. The physiological conditions of the gastrointestinal tract and the physicochemical properties of drugs are being considered to develop strategies and approaches to overcome emerging challenges. This review will discuss factors, challenges, strategies, and approaches to developing a colon-targeted drug delivery system.

Copyrights © 2022






Journal Info

Abbrev

publication:psr

Publisher

Subject

Description

Aims Pharmaceutical Sciences and Research (PSR), an international, peer-reviewed, open access, and official journal from Faculty of Pharmacy, Universitas Indonesia, aims to disseminate research results and findings in Pharmaceutical Sciences and Practices. Major area of interest is natural products ...