Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy)
JURNAL ILMU FARMASI & FARMASI KLINIK VOL. 13 NO. 1 JUNI 2016

PENELUSURAN POTENSI AKTIVITAS SITOTOKSIK FRAKSI KULIT BATANG TUMBUHAN FALOAK (Sterculia quadrifida R.Br)

Rollando Rollando (Unknown)
Siswadi Siswadi (Unknown)



Article Info

Publish Date
01 Jun 2016

Abstract

ABSTRACT People on Timor island use Faloak (Sterculia quadrifida R.Br.) bark as herbal remedy to cure diseases such as liver diseases, gastroenteritis and as stamina booster. This study aims to analyze the ability of anticancer fraction of faloak bark ethanol extract.  The mashed  bark of  faloak  plants extracted by maceration method using ethanol. The ethanol extract fractionated using preparative thin layer chromatography with  mixture  mobile phase which, chloroform, n-butanol, ethyl acetate with ratio (3: 4: 1,5). Chromatogram detected with visible light, UV254, UV366, and cerium sulfate reagent, then marked. Fraction obtained five fractions.  Cytotoxic  test against T47D cell and Vero cell  conducted using MTT, IC50  and selectivity sndex (SI) used as an anticancer efficacy parameter. Fraction 4  showed moderate anticancer activity with IC50 of 21.89 μg/mL in T47D cell line. Keywords: Faloak bark, anticancer activiy, T47D cell line

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Journal Info

Abbrev

Farmasi

Publisher

Subject

Medicine & Pharmacology

Description

Selamat datang di situs e-Publikasi Ilmiah Fakultas Farmasi Unwahas (Universitas Wahid Hasyim) Semarang. Situs ini berisi kumpulan publikasi ilmiah yang diterbitkan oleh Fakultas Farmasi Unwahas. Publikasi berasal dari jurnal-jurnal serta hasil prosiding seminar yang dilaksanakan oleh Fakultas ...