PENDIPA Journal of Science Education
Vol 6 No 3 (2022): July - October

A ANTI-DIABETIC ACTIVITY OF SIMBAGH UTAK (Hydnophytum formicarum) tuber extract on the blood sugar level of mice (Mus muscullus) MALE INDUCED ALLOXAN: AKTIVITAS ANTI DIABETES EKSTRAK UMBI SIMBAGH UTAK (Hydnophytum formicarum) TERHADAP KADAR GULA DARAH MENCIT (Mus muscullus) JANTAN DIINDUKSI ALOKSAN

Mayshah Purnamasari (a:1:{s:5:"en_US"
s:18:"Universitas Sutomo"
})

Aceng Ruyani (Universitas Bengkulu)
Agus Sundaryono (Universitas Bengkulu)



Article Info

Publish Date
03 Nov 2022

Abstract

Medicinal plants ant nests or simbagh utak (Hydnophytum formicarum) are found in the Bengkulu area south of Bengkulu province. Simbagh utak tubers (H. formicarum) can empirically treat headaches, bruises and aches. H. formicarum also has cytotoxic, antioxidant and antibacterial activity. The purpose of this study was to determine the antidiabetic activity of the ethanolic extract of the medicinal plant simbagh utak (H. formicarum) against alloxan-induced mice, and Phytochemical Test to determine the content of secondary metabolites contained in the extract. The extract was obtained by maceration by soaking simbagh utak powder (H. formicarum) with 96% ethanol as solvent. The solvent contained in the ethanolic extract of simbagh utak (H. formicarum) was evaporated using a rotary evaporator to obtain ethanolic extract of simbagh utak (H. formicarum). Furthermore, the ethanolic extract of simbagh utak (H. formicarum) was tested on mice that had been induced by alloxan. The results showed that after the ANOVA and T-student statistical tests were carried out, it could be stated that the tuber extract of the Simbagh Utak (H. formicarum) plant was seen to be very significant in reducing blood sugar levels of male mice (Mus musculus) that had been induced by alloxan at a dose of 0.7056 g. /kg BW, and tuber extract of H. formicarum contained flavonoid and phenolic compounds. Flavonoid and phenolic compounds can act as free radical scavengers.

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Journal Info

Abbrev

pendipa

Publisher

Subject

Chemistry Education Mathematics

Description

PENDIPA Journal of Science Education is a peer-reviewed, open-access journal covered all aspect of science and science education. PENDIPA journal welcomes the submission of scientific articles related to mathematics, physics, chemistry, biology, and its educational implementation in a school, higher ...