ISM (Intisari Sains Medis) : Jurnal Kedokteran
Vol. 12 No. 2 (2021): (Available Online: 1 August 2021)

Neutrophil-Lymphocyte Ratio (NLR) as an output-outcome predictor in moderate-severe head injury at Sanglah General Hospital, Denpasar, Indonesia

Melissa Krisanty (Resident of Surgery, Medical Faculty, Universitas Udayana, Sanglah General Hospital, Denpasar, Indonesia)
Tjokorda Gde Bagus Mahadewa (Department of Surgery, Neurosurgery Division, Medical Faculty, Universitas Udayana, Sanglah General Hospital, Denpasar, Indonesia)
I Wayan Niryana (Department of Surgery, Neurosurgery Division, Medical Faculty, Universitas Udayana, Sanglah General Hospital, Denpasar, Indonesia)
I Nyoman Semadi (Department of Surgery, Thoracic and Cardiovascular Division, Medical Faculty, Universitas Udayana, Sanglah General Hospital, Denpasar, Indonesia)
I Gede Suwedagatha (Department of Surgery, General Surgery Division, Medical Faculty, Universitas Udayana, Sanglah General Hospital, Denpasar, Indonesia)
I Gusti Agung Bagus Krisna Wibawa (Department of Surgery, General Surgery Division, Medical Faculty, Universitas Udayana, Sanglah General Hospital, Denpasar, Indonesia)



Article Info

Publish Date
10 Aug 2021

Abstract

Background: This prospective cohort study aims to determine the best cut point value and the ability to predict Neutrophil Lymphocyte Ratio (NLR), analyze the most dominant factors, and the direct influence of the NLR to output and outcome in moderate and severe trauma to the head injury at Sanglah General Hospital, Denpasar, Indonesia.Methods: This study was an observational analytic with a prospective cohort design. The subjects of this study were head injury patients over 16 years old with Glasgow Coma Scale (GCS) ? 12 who visited and were treated at Sanglah General Hospital, Denpasar, Indonesia. Patients less than 16 years old, history of alcohol intoxication, stroke, metabolic disease, and multiple traumas were not included as research subjects. Data were analyzed using SPSS version 20 for Windows.Results: The research conducted on 49 respondents found that the best cut-off point of NLR was 6.05 has the most significant predictor (OR=7.6; p=0.001) and dominant (OR=64.97; p=0.002) factors to the output-outcome predictor in moderate-severe head injury. In addition, this cut-off value (6.05) also has a direct influence (x-value=0.523) in the occurrence of output and outcome unfavorable in moderate-severe head injury.Conclusion: the cut-off NLR values of 6.05 became the dominant predictor that directly affected the output and outcome unfavorable in moderate-severe head injury.

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Journal Info

Abbrev

ism

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Description

Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and ...