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ISM (Intisari Sains Medis) : Jurnal Kedokteran

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Published by Universitas Udayana

ISSN : 25033638 EISSN : - DOI : -

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Intisari Sains Medis is published by Medical Scientific Community, Indonesia. Intisari Sains Medis is an international, multidisciplinary, peer-reviewed, open access journal accepts papers for publication in all aspects of Science Digest, Medical Research Development, Research Medical Field and Theory. We also publish cases from third world country, that is considered very rare and special cases.

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Articles 1,063 Documents

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Anak laki-laki usia 4 tahun dengan paraparesis lower motor neuron, gizi kurang, pendek, dan masalah makan di RS tipe B: sebuah laporan kasus Fitriana Melinda; Made Ratna Dewi
Intisari Sains Medis Vol. 12 No. 3 (2021): (Available online: 1 December 2021)
Publisher : DiscoverSys Inc.

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Background: Paralysis is a symptom of various diseases, disorders, or certain conditions, ranging from mild to severe and can be caused by infectious processes, trauma, malignancies, autoimmune diseases, and other abnormal processes. Eating problems in children is one of the developmental disorders that can occur in healthy infants or children. Eating problems have the potential to cause cognitive and behavioral disorders, and are associated with anxiety disorders and eating disorders in children, adolescents, and young adults. Case description: A 4 years 2 months old male, complained not being able to walk and his legs shrinking since 2 weeks of SMRS. His male cousin has experienced paralysis of the right leg since the 3rd grade of elementary school. There were multiple enlarged right inguinal lymph nodes accompanied by refusal to take meal for the past 3 months. Neurological examination found normal energy in all four extremities but decreased patellar and achilles reflex. Body weight (BW) was 11 kg, body length (BL) 94 cm, BW/BL (-3) - (-2) SD (wasted). Leukocytes 6.4/ul, hemoglobin 11.0 g/dl, hematocrit 33.3%, MCV 69.4 fl, MCH 22.9 pg, MCHC 33.0 g/L, platelets 396.000 /ul, ESR 41 mm / hours, CRP 11 mg/L and CK 1,441 U/L. Radiological examination of lumbosacral photo showed the impression of paraspinal muscle spasm. The patient diagnose with lower motor neuron paraparesis. Conclusion: Handling of patients with eating problems and LMN paraparesis is given non-medical management by meeting fluid needs, nutrition according to patient needs and education about feeding rules to the patient's parents, consultation with psychologists, and medical rehabilitation seek treatment. improvement of eating problems and medical problems in the form of weak legs more optimally. Latar belakang: Kelumpuhan adalah gejala dari berbagai penyakit, kelainan, atau kondisi tertentu, mulai dari yang ringan sampai berat, yang disebabkan oleh proses infeksi, trauma, keganasan, penyakit autoimun, dan proses abnormal lainnya. Masalah makan pada anak merupakan salah satu gangguan perkembangan yang dapat terjadi pada bayi atau anak sehat. Selain itu, masalah makan berpotensi menyebabkan gangguan kognitif dan perilaku, serta dikaitkan dengan gangguan cemas dan kelainan makan pada anak, remaja, dan dewasa muda. Deskripsi kasus: Anak laki-laki berusia 4 tahun 2 bulan, keluhan tidak bisa berjalan dan kaki mengecil sejak 2 minggu SMRS. Kakak sepupu laki-laki dari ibu pasien mengalami kelumpuhan kaki kanan sejak kelas 3 SD. Ditemukan adanya pembesaran kelenjar getah bening inguinal dekstra multipel disertai tidak mau makan sejak 3 bulan lalu. Pemeriksaan neurologis didapatkan tenaga normal pada keempat ekstremitas namun penurunan refleks fisiologis kniepeesreflex (KPR) dan achillespeesreflex (APR). Status antropometri yaitu BB 11 kg, PB 94 cm, BB/PB (-3)-(-2) SD (wasted). Leukosit 6.4 /ul, hemoglobin 11.0 g/dl, hematokrit 33,3%, MCV 69,4 fl, MCH 22,9 pg, MCHC 33,0 g/L, trombosit 396.000/ul, LED 41 mm/jam, CRP 11 mg/L dan CK 1,441 U/L. Radiologi lumbosakral antero-posterior/lateral didapatkan kesan paraspinal muscle spasm. Pasien didiagnosis paraparesis lower motor neuron (LMN). Simpulan: Penanganan pasien dengan anak dengan masalah makan dan paraparesis LMN diberikan penatalaksanaan non-medikamentosa dengan pemenuhan kebutuhan cairan, nutrisi sesuai kebutuhan pasien dan edukasi mengenai feeding rules kepada orang tua pasien, konsultasi dengan psikolog, serta rehabilitasi medik untuk mengupayakan perbaikan masalah makan dan masalah medis berupa kaki lemas dengan lebih maksimal.

Studi deskriptif kasus malaria sebelum dan sesudah gempa di Kecamatan Gunung Sari, Lombok Barat, Indonesia Ni Luh Made Mirah Rahayu; Indah Sapta Wardani; Dewi Suryani; Ni Luh Putu Harta Wedari
Intisari Sains Medis Vol. 13 No. 3 (2022): (In Press 1 December 2022)
Publisher : DiscoverSys Inc.

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Background: Indonesia is the country where malaria transmission still occurs. Malaria disease transmission has increased, for example when an earthquake occurred in Lombok. This research aims to explore the comparison of malaria cases in Gunung Sari District before and after the Lombok earthquake. Methods: Primary data were obtained by filling in the online google form by the interviewees and then continued by interviewing on telephone. Secondary data were obtained from online medical records from the information section of Gunung Sari and Penimbung Health Center, West Lombok. Results: Malaria incidence 6 months before the earthquake was 16 cases with the dominant type of malaria, namely P. falciparum malaria, and 6 months after the earthquake was 830 cases with the dominant type of malaria, namely mixed Plasmodium malaria (P. falciparum and P. vivax). Malaria incidence 1 year after the earthquake was 8 cases with the dominant type of malaria, namely P. falciparum. Efforts to reduce malaria cases include eradicating mosquitoes, increasing public awareness, early diagnosis of malaria, monitoring treatment, and using bed nets. Conclusion: Malaria incidence has increased in the 6 months after the earthquake because of loss of homes and post-disaster ecological changes. Malaria incidence 1 year after the earthquake has decreased. Efforts to reduce cases include eradication of mosquitoes, public knowledge, and environment restoration. Latar Belakang: Indonesia merupakan salah satu negara dimana masih terjadi transmisi malaria. Penularan penyakit malaria meningkat pada populasi yang terkena bencana contohnya gempa yang terjadi di Lombok. Penelitian ini bertujuan mengetahui perbandingan kasus malaria di Kecamatan Gunung Sari sebelum dan sesudah gempa Lombok. Metode: Data primer diperoleh dengan pengisian google form secara daring oleh narasumber lalu dilanjutkan wawancara melalui sambungan telepon. Data sekunder diperoleh dari data rekam medis secara daring dari bagian informasi Puskesmas Gunung Sari dan Penimbung, Lombok. Hasil: Angka kasus malaria 6 bulan sebelum gempa adalah 16 kasus dengan jenis malaria dominan yakni malaria P. falciparum. Sedangkan angka kasus malaria 6 bulan sesudah gempa adalah 830 kasus dengan jenis malaria dominan yakni malaria Plasmodium campuran (P. falciparum dan P. vivax). Angka kasus malaria 1 tahun pasca gempa tersebut adalah 8 kasus dengan jenis malaria dominan yakni P. falciparum. Upaya penurunan kasus malaria meliputi pemberantasan nyamuk, peningkatan wawasan masyarakat, diagnosis dini malaria, pemantauan pengobatan, dan penggunaan kelambu. Simpulan: Angka kasus malaria mengalami peningkatan pada 6 bulan sesudah gempa Lombok. Faktor yang meningkatkan penularan penyakit malaria ini adalah kehilangan rumah dan perubahan ekologi pasca bencana. Sedangkan angka kasus malaria 1 tahun pasca gempa Lombok mengalami penurunan. Upaya penurunan kasus yakni pemberantasan nyamuk, pengetahuan masyarakat, dan pemulihan lingkungan tempat tinggal korban bencana.

Hubungan komunikasi efektif dokter-pasien terhadap tingkat kepuasan pasien dalam pelayanan medik Dahliana Jessica Aristy Silaen; Ibnu Alferraly
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Introduction: Indonesia is the biggest contributor of medical tourists to Malaysia and Singapore in recent years, mostly from Medan. Literature reviews and experts opinion of community medicine revealed that poor doctorsâ€™ communication skills in Indonesia lead to decreased patients satisfaction and lead to the number of patients seeking treatment abroad.Aim: This study aimed to analyze the relationship between physician-patient communication on the level of patient satisfaction in Central Public Hospital Haji Adam Malik, Medan.Method: This research uses a combination of descriptive-analytic study with cross sectional design. Statistical analysis was performed by chi-square test. The sample selection of research done by consecutive sampling. Measurement doctor-patient communication and patient satisfaction rate is determined by using modified CAT (Communication Assessment Tool) questionnaire.Result: Ten outpatient clinics of Central Public Hospital Haji Adam Malik (10 patients per outpatient clinic) participated in the field test. The average mean score was 4.086 across all modified CAT items (SD = 0.609, range 2.23-5.00). The average proportion of satisfaction rate was 81.7% (S.D. = 12.19, range 44.62-100%). There was a significant relationship between physician-patient communication with patient satisfaction (p <0.05).Conclusion: Assessment doctor-patient communication in Outpatient Clinics of Central Public Hospital Haji Adam Malik categorized as good. Patient satisfaction rate in Outpatient Clinics of Central Public Hospital Haji Adam Malik categorized as satisfied. Effective physician-patient communication associated with patient satisfaction with the physician.

Disregulasi IL-17, CD4 neutrofil, IL-10, PGE-2, iNOS, dan MMP-9 di jaringan kulit terhadap kerusakan saraf dermal pada pasien erythema nodusum leprosum I Gusti Nyoman Darmaputra; Cita Rosita Sigit Prakoeswa; Anang Endaryanto; IGAA Elis Indira; Nyoman Suryawati; Evy Ervianti; Linda Astari; Bagus Bagus
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Introduction: The mechanism of nerve damage in ENL patients is important to be revealed because the problem of nerve damage is not getting enough attention in handling ENL patients. Some pro-inflammatory mediators that have been studied are risk factors for nerve damage in ENL.Aim: This study aim in knowing the mechanism of nerve damage in the relation with its risk factors, which are CD64 neutrophil, IL-17, MMP-9, and iNOS with PGE-2 and IL-10 protective factor and IL-10 in ENL patients.Method: This is an analytic cross-sectional design study with tissue samples from 30 leprosy patients with ENL in Dr. Soetomo General Hospital Surabaya. Samples from biopsy examined using IHC method to evaluate S-100, IL-10, IL-17, PGE-2, iNOS, MMP-9, and CD64 neutrophil expressions. The result calculated within 20 view field with 1000 times magnification.Result: CD64 neutrophil (p=0.022, r=-0.417), IL-17 (p=0.001, r=-0.560), iNOS (p=0.005, r=-0.502) and MMP-9 (p=0.025, r=-0.409) has significant correlation with S-100. There is no significant correlation between IL-10 (p=0.061) and PGE-2 (p=0.407) with S-100.Conclusion: Expressions of IL-17, CD64 neutrophil, MMP-9, and iNOS in tissue correlate with nerve damage in ENL patients.

Hubungan proteinuria dan batu saluran kemih: studi analitik Zulfikar Ali; Eko Arianto
Intisari Sains Medis Vol. 11 No. 1 (2020): (Available online: 1 April 2020)
Publisher : DiscoverSys Inc.

Latar Belakang: Batu saluran kemih (BSK) masih merupakan salah satu masalah tersering yang dihadapi urolog. Proteinuria dapat ditemukan pada kondisi gagal ginjal kronis (GGK), infeksi saluran kemih (ISK), keganasan, ataupun BSK. Protein urin diketahui berperan dalam proses supersaturasi dan agregasi BSK. Studi terkini menemukan hubungan protein marker urin dengan BSK pada level molekular setelah proses elektroforesis. Penelitian ini bertujuan untuk mengetahui hubungan proteinuria pada urinalisa dengan BSK.Metode: Penelitian ini adalah penelitian studi potong lintang dengan subjek pasien poli urologi di RSUD Kardinah, Tegal. Total sampel 200 pasien yang dikelompokkan menjadi 100 pasien BSK dan 100 pasien kontrol. Seluruh pasien dilakukan pemeriksaan ultrasound (USG) sebagai pemeriksaan diagnosis awal, kemudian dilakukan pemeriksaan urinalisa. Proteinuria dianggap positif untuk nilai protein urin +1 sampai +4 dan negatif pada nilai protein urin trace dan negatif. Variabel lain yang dianalisa adalah ISK, ph urin, usia, dan jenis kelamin.Hasil: Pasien laki-laki memiliki kecenderungan BSK yang lebih tinggi dibandingkan perempuan dengan rasio 1,8:1. Rentang usia kelompok BSK 23-78 tahun dan pada kelompok kontrol 17-85 tahun. Tidak didapatkan hubungan yang bermakna antara proteinuria dengan BSK (p = 0,203). Terdapat hubungan antara ISK dengan BSK (p = 0,002) dan ph urin dengan BSK (p = 0,024). Terdapat hubungan antara ISK dengan proteinuria pada uji univariat dan multivariat (p = 0,000).Kesimpulan: Tidak didapatkan hubungan antara proteinuria dengan BSK. Terdapat hubungan antara proteinuria dengan ISK. Proteinuria muncul karena proses inflamasi pada kasus infeksi akibat batu. Penelitian lanjutan diperlukan untuk menentukan jenis protein urin yang menjadi inhibitor pada pasien non stone former dan jenis protein urin yang ditemukan pada stone former.

Hubungan konsumsi kopi hitam terhadap tekanan darah pada perokok dewasa Ni Made Sarah Manacika Naraswari; I Wayan Gde Sutadarma; Ni Nyoman Ayu Dewi
Intisari Sains Medis Vol. 11 No. 3 (2020): (Available online: 1 December 2020)
Publisher : DiscoverSys Inc.

Background: Unhealthy lifestyles such as smoking and consuming coffee can affect blood pressure.Aim: The study aims to evaluate the association between black coffee consumption and hypertension.Method: This study design was cross-sectional with 93 participants. Data taken from questionnaire measurements and blood pressure measurements at a time.Results and conclusion: The results showed 79.6% had abnormal blood pressure and 20.4% had normal blood pressure. In this study male smoker workers who consumed black coffee were statistically related to blood pressure (p <0.05). Pola hidup yang tidak sehat seperti merokok dan mengkonsumsi kopi dapat mempengaruhi tekanan idarah.Tujuan: Untuk mengevaluasi hubungan konsumsi kopi hitam dan tekanan darah.Metode: Desain penelitian ini cross-sectional dengan 93 peserta sampel. Data yang diambil berasal dari pengukuran kuisioner dan pengukuran tekanan darah sewaktu.Hasil dan simpulan: Terdapat 79,6% sampel memiliki tekanan idarah tidak normal dan 20,4% memiliki tekanan darah normal. Dalam penelitian ini pekerja laki-laki perokok yang mengkonsumsi kopi hitam berhubungan secara statistik dengan tekanani darah (p < 0,05).

The association between overweight and shock in children with dengue hemorrhagic fever at Wangaya General Hospital, Bali, Indonesia Jade Irene Linardi; I Wayan Bikin Suryawan; Anak Agung Made Widiasa
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Background: Dengue Hemorrhagic Fever (DHF) which severity varies, has devastating complications and outcomes, especially when shock events appeared and are prolonged. There is no predictor of whether DHF patients would develop into shock (called Dengue Shock Syndrome or DSS). Previous studies claimed overweight as a predictor of DSS, although it remains controversial.Objective: To find the association between overweight and shock events in children with DHF.Methods: This was an observational analytic study with a case-control design. Data were taken from medical records with children hospitalized at Wangaya General Hospital from May 2019 through April 2020. Inclusion criteria were children < 18 years who have been diagnosed with DHF grade I through IV. Data were analyzed using the chi-square test in SPSS 24.0 for windows.Results: Of 126 subjects who fulfilled the inclusion criteria, there were 42 DSS patients as the case group and 84 non-DSS patients as the control group. From the data analysis, there was a significant association between overweight and shock events in children with DHF (p=0.001; OR 3.76; 95% CI 1.72 to 8.20). Furthermore, pleural effusion (p=0.001), highest hematocrit of ? 46% (p=0.001), and lowest platelet count of ? 50,000/µL (p=0.006) also had significant association with shock events.Conclusion: Overweight is associated with shock events in children with DHF. Pleural effusion, hematocrit level of ? 46%, and platelet count of ? 50,000/µL were also counted as risk factors to develop shock.

Surgical excision with paramedian forehead flap reconstruction in recurrent basal cell carcinoma of the nose Nathan Aditya Willyanto; Samsul Huda
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Background: Basal cell carcinoma (BCC) is the most common malignancy worldwide, especially in fair-skinned people. Along with squamous cell carcinoma (SCC), these malignancies are grouped as non-melanoma skin cancer (NMSC). The nose is a common site for BCC because it is exposed to the sun. The rates of recurrence are variable in the literature, between 10% and 67%. The ideal surgical treatment for BCC is complete tumor removal with safety margins. Wide excision of the BCC will leave the nose with a soft tissue defect and sometimes part of cartilage or skeleton, which requires nasal reconstruction.Case presentation: An 80-year-old female was admitted to the General Surgery Department of Soebandi General Hospital Jember presenting with ulceration on the right side of her nose 4 months before admission. The patient had a previous history of surgical excision on the nose 15 years ago on the nose's left side.Conclusion: Recurrent cases of BCC are still the main issue in treating BCC. Wide excision of the BCC will leave the nose with a soft tissue defect, which requires nasal reconstruction. The paramedian forehead flap is recommended for defect closure in nasal reconstruction.

Karakteristik pasien kebidanan dengan infeksi COVID-19 di Ruang Praja RSUD Wangaya Bali periode Mei - Desember 2020 Johan Qalaba; Gede Alit Wardana
Intisari Sains Medis Vol. 12 No. 1 (2021): (Available online : 1 April 2021)
Publisher : DiscoverSys Inc.

Background: Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the SARS-COV2 virus. Pregnant women are important because pregnant women are more susceptible to viral infections and severe pneumonia due to physiological changes in the immune and cardiopulmonary systems during pregnancy, with manifestations ranging from asymptomatic to very severe. At this time, no research has been conducted on the local population, so that the authors will examine the characteristics of obstetric patients with COVID-19 infection in the Praja room of RSUD WANGAYA Bali. To determine the characteristics of midwifery patients with COVID-19 infection in the Praja room at Wangaya Bali Hospital for the period May 2020 - December 2020.Methods: This study was a retrospective descriptive study using medical records from mothers related to COVID-19. The inclusion criteria were obstetric patients with COVID-19 infection in the Praja room with the results of a reactive Rapid Test or RT-PCR at Wangaya Hospital. The data collected were age, parity, screening rapid test, comorbid, probable case, clinical symptoms, laboratory results, chest x-ray, baby weight and APGAR score, type of delivery, amount of postpartum hemorrhage, confirm case with RT-PCR, length of treatment, the need for ICU rooms and the number of deaths.Results: In this study, there were 67 respondents. Most of them were in the age range of 21-30 years and had given birth more than once. More than half of the respondents had a cesarean section, and most of the respondents tested positive for COVID-19 through the RT-PCR test. APGAR scores and baby weight were mostly normal. There were 62 respondents confirmed as RT-PCR, while with the Rapid reactive results, 66 people. Patients with mild anemia were found and found an increase in the number of CRP and neutrophils. Asymptomatic and non-comorbid patients were the most common, and on the x-ray image, most had pneumonia. There was no postpartum hemorrhage in either method of delivery. Only one person needs an ICU room. Patients infected with COVID-19 require a longer treatment time.Conclusion: Most were found in no comorbid and asymptomatic. Laboratory results were mostly found with mild anemia, leukocytosis with neutrophilia and high NLR, and high CRP. Most pregnant women do not need ICU care. Latar belakang: Penyakit corona virus 2019 (COVID-19) merupakan penyakit yang sangat menular yang disebabkan oleh virus SARS-COV2. Wanita hamil penting untuk diperhatikan karena wanita hamil lebih rentan terhadap infeksi virus dan pneumonia parah akibat adanya perubahan fisiologis pada sistem imun dan cardiopulmonal selama kehamilan, dengan manisfestasi dari tanpa gejala hingga sangat berat. Pada saat ini belum ada penelitian yang di lakukan pada populasi lokal, sehingga penulis akan meneliti karakteristik pasien kebidanan dengan infeksi COVID-19 di ruang Praja RSUD WANGAYA Bali. Untuk mengetahui karakteristik pasien kebidanan dengan infeksi COVID-19 di ruang Praja RSUD Wangaya Bali periode Mei 2020 - Desember 2020.Metode: Penelitian deskriptif retrospektif dengan data catatan medik dari ibu terkait COVID-19. Kriteria inklusi merupakan pasien kebidanan dengan infeksi COVID-19 di ruang Praja dengan hasil Rapid Test atau RT-PCR reaktif di RSUD Wangaya. Data yang dikumpulkan adalah usia, paritas, skrining rapid test, komorbid, probable case, gejala klinis, hasil laboratorium, ronsen thorax, berat badan dan skor APGAR bayi, jenis persalinan, jumlah perdarahan post partum, confirm case dengan RT-PCR, lama perawatan, kebutuhan ruang rawat ICU dan jumlah yang meninggal.Hasil: Pada penelitian ini terdapat 67 responden, sebagian besar berada dalam rentang usia 21-30 tahun dan sudah pernah melahirkan lebih dari satu kali. Lebih dari separuh responden jenis persalinannya merupakan seksio sesaria, dan sebagian besar responden positif COVID-19 melalui tes RT-PCR. Skor APGAR dan berat badan bayi sebagian besar normal. Terdapat 62 responden terkonfirmasi RT-PCR, sedangkan dengan hasil Rapid reaktif, sebanyak 66 orang. Ditemukan pasien dengan keadaan anemia ringan, serta di dapatkan adanya peningkatan jumlah CRP dan Neutrofil. Pasien tanpa gejala dan tanpa komorbid paling banyak dijumpai dan pada gambaran ronsen terbanyak mengalami pneumonia. Tidak terdapatnya perdarahan post partum pada kedua metode persalinan. Hanya 1 orang yang memerlukan ruangan ICU. Pasien terinfeksi COVID-19 memerlukan waktu perawatan yang lebih lama.Kesimpulan: Sebagian besar ditemukan dalam tanpa kmorbid dan tanpa gejala. Hasil laboratorium sebagian besar ditemukan dengan anemia ringan, leukositosis dengan neutrofilia dan NLR tinggi, serta CRP tinggi. Sebagian besar ibu hamil tidak mebutuhkan perawatan ICU.

Analisis tingkat pengetahuan mahasiswa program studi pendidikan dokter tahun ajaran 2017-2018 Universitas Udayana tentang prescribing error Nabila Putri Rachmawati; Desak Ketut Ernawati; I Gusti Ayu Artini
Intisari Sains Medis Vol. 10 No. 1 (2019): (Available online 1 April 2019)
Publisher : DiscoverSys Inc.

Introduction: Prescribing Errors is a failure in the treatment process leading to or potentially harmful to the patient, this error most often occurs although it can be prevented. The incidence of prescribing errors continues to increase from year to year, but data in Indonesia that discusses the level of knowledge of medical students about prescribing errors is still small. The purpose of this study is to determine the level of knowledge of medical student study program 2017-2018 academic year at Udayana University Denpasar about prescribing errors.Method: This research is a descriptive cross sectional study conducted at the Medical Faculty Udayana University Sudirman Campus Denpasar. Data obtained in the form of primary data questionnaire. Data were analyzed using software computer.Result: The results showed that the most gender are women of 68 students (66%). The largest proportion of age is 19-20 years old number of 52 students (52%). Groups of semesters 1, 3, 5 and 7 obatined a similar proportion of 25 students (25%). The level of students' knowledge of prescribing case study is classified into moderate category with mean 3,7-7,1 of 67 students (67%). The number of correct answers in identifying type of error from 3 prescriptions is in the case of the first prescription, the 3rd semester student who is able to identify the prescribing error, with the type of mistake that is wrong dose as many as 14 students (35,9%) with p value = 0,066 and wrong dosage form as 21 students (39,6%) with p value = 0.000. In the case of the second prescriptions, 7th semester students were able to identify the prescribing error, with the type of mistake that is wrong dose as many as 13 students (41,9%) with p value = 0,005 and wrong dosage form as 22 students (36,7%) with p value = 0.000. In the case of the third prescriptions, the 3rd semester students were able to identify the prescribing error, with the type of mistake that is the wrong indication of the drug as many as 15 students (62,5%) p value = 0.000.Conclusion: In this research, it can be concluded that the knowledge level of the majority students is in moderate levelabout 67 (67%). While the remaining respondents good knowledge level as much as 7 (7%) and bad knowledge is as much as 26 (26%).

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