Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science)
Vol 19, No 2: September 2022

Formulation of self-nano emulsifying drug delivery system (SNEDDS) Red Ginger extract (Zingiber Officinale var. rubrum)

Mila Erliyana (Ahmad Dahlan University)
Wahyu Widyaningsih (Farmasi. Universitas Ahmad Dahlan)
Dea Anggrainy Wumu (Farmasi, Universitas Ahmad Dahlan)
Widyanari Febriyana Wulansari (Farmasi, Universitas Ahmad Dahlan)



Article Info

Publish Date
14 Sep 2022

Abstract

Red ginger extract is one of the new medicinal discoveries made from natural substances that has pharmacological benefits in the treatment of diabetes. Many gingerol components in red ginger can aid in the treatment of diabetes mellitus. However, the administration of red ginger extract is not so effective, a delivery system such as SNEDDS (Self-Nano Emulsifying Drug Delivery System) must be developed. When compared to standard formulations, SNEDDS can boost the oral bioavailability of lipophilic medicines by up to 2.4 times. The oil phase of SNEDDS red ginger extract was virgin coconut oil, with tween 80 as a surfactant and PEG 400 as a co-surfactant. The fourth formula of the SNEDSS preparation of red ginger rhizome extract satisfied the requirements for a good nanoemulsion particle size in this study, with a percent T value of 99.7% and PSA test data showing that this formulation met the requirements for a good nanoemulsion particle size

Copyrights © 2022






Journal Info

Abbrev

Media-Farmasi

Publisher

Subject

Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

Description

Media Farmasi is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Media Farmasi published two times a year, namely in March and September since 2002 with ISSN 1412-7946 and e-ISSN 2503-5223. The article published in the Journal ...