Majalah Kedokteran Andalas
Vol 45, No 4 (2022): Online October 2022

Differences in Levels of 25-hydroxyvitamin D, Human Chorionic Gonadotropin (hCG), and Progesterone in Normal Pregnancy and First Trimester Abortion

Afkara Husna Firdanisa (Master Program in Biomedical Sciences, Faculty of Medicine, Andalas University)
Fika Tri Anggraini (Department of Physiology, Faculty of Medicine, Andalas University)
Bobby Indra Utama (Sub Division of Urogynecology, Obstrectics and Gynecology Department, Faculty of Medicine, Andalas University, Dr. M. Djamil Central General Hospital Padang)



Article Info

Publish Date
12 Oct 2022

Abstract

Early pregnancy failure was defined as the failure of an intrauterine pregnancy less than 12 weeks old.This research is a comparative analytic study with  a  cross   sectional    approach. the sampling technique was consecutively taken. The normality of data was tested with the Saphiro Wilk test and data analysis with the Independent T test.Vitamin D levels were significantly higher in normal pregnancies than in the abortion group, in line with vitamin D levels as well as hCG levels and progesterone levels were significantly higher in normal pregnancies than in the abortion group. This explains the theory that vitamin D in trophoblast plays a role in regulating the production of hCG and progesterone.The conclusion in this study was that the average level of 25-hydroxyvitamin D, Human Chorionic Gonadotropin(hCG), and Progesterone were significantly different between normal pregnancies and pregnancies that had abortions in the first trimester.

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Journal Info

Abbrev

art

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

Majalah Kedokteran Andalas (MKA) (p-ISSN: 0126-2092, e-ISSN: 2442-5230) is a peer-reviewed, open-access national journal published by Faculty of Medicine, Universitas Andalas and is dedicated to publish and disseminate research articles, literature reviews, and case reports, in the field of medicine ...