Indonesian Journal of Multidisciplinary Science
Vol. 2 No. 3 (2022): Indonesian Journal of Multidisciplinary Science

Kersen Leaf Tea’s Effects on Male Mice’s Liver and Kidney Functions Induced by Alloxan

Wiyadi Wiyadi (Department of Nursing, Politeknik Kesehatan Kalimantan Timur, Samarinda, East Kalimantan)
Mustaming Mustaming (Department of Laboratory Engineering, Politeknik Kesehatan Kalimantan Timur, Samarinda, East Kalimantan)
Rus Andraini (Department of Nursing, Politeknik Kesehatan Kalimantan Timur, Samarinda, East Kalimantan)



Article Info

Publish Date
11 Dec 2022

Abstract

Kersen leaf is a tree native to Southern America and Southern Mexico. In Indonesia, this tree is very easy to get because it grows a lot on the side of the streets. Empirically, Kersen leaves have been widely used by the public as one of the herbs or herbs to overcome various diseases, including DM disease. The study used True Experimental design with Pre and post Control Design design. The purpose of this study  was to test the effect of using Kersen Leaf Tea on Hepar and Kidney function. Hepar function will be measured by assessing levels of Alanain Transminerase (ALT) Aspartate aminotransferases (AST). For kidney function is assessed by measuring Creatinine and Ureum levels. The results of  the Shapiro test  normality test obtained data that were not normally distributed so that the Bivariate test used alternative tests, namely  the Kruscal Walis test and the Wilcoxon Test. The results of the study on the administration of kersen leaf tea there were differences between the Control group with the dose group of 2%, dose 4% and dose 6% at ALT levels (p = 0.000), AST levels (p = 0.005), and creatinine levels (p = 0.007) but there was no difference in Urium (P = 0.447). The results of the Wilcoxon test showed the effect of giving kersen leaf tea on ALT levels ( p = 0.018), AST levels (p = 0.000), Urium levels (p = 0.37) and creatinine levels (p = 0.038). The administration of kersen leaf tea improves liver and kidney function in Alloxan-induced male mice.

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Journal Info

Abbrev

ijoms

Publisher

Subject

Humanities Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Public Health Social Sciences

Description

Indonesian Journal of Multidisciplinary Science (IJOMS) is a scientific journal in the form of research and can be accessed openly. This journal has e-ISSN 2808-6724 and p-ISSN 2808-5957. This journal is published monthly by International Journal Labs. The development of the company made the ...