MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan
Vol 10, No 1 (2023): February

Diabetic Wound Healing Activity of Anabas testudineus Fish Scales

Erwin Rosadi (Faculty of Fishery and Marine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia)
Lia Yulia Budiarti (Faculty of Medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia)
Bhisma Ridho Romadhon (Faculty of Medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia)
Nida Nurkhalishah (Faculty of Medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia)
Nur Salsabila Apriliani Risma Putri (Faculty of Medicine University of Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia)
Nur Azmina Aisyah (Sepuluh Nopember Institute of Technology, Surabaya, East Java, Indonesia)
Isnaini Isnaini ([Scopus ID: 57204801189] FK Universitas Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia)



Article Info

Publish Date
01 Feb 2023

Abstract

Background:  Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing.Objective: This study aimed to extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gelMethods: Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl, and 50% NaOH. FTIR will analyze the extraction results to see the functional groups of the extract. Activity test of fish scale extracts diabetic wound healing gel was carried out on Rattus novergicus Wistar strain for 14 days. There were five treatments: negative control, positive control given octenillinR, and fish scale extract gel conc. 5%, 10%, and 15%.Results: The results showed that the fish scales extract contained chitosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%. Conclusion: A. testudineus fish scale extract contains chitosan, as seen from the FTIR results.

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Journal Info

Abbrev

APKKM

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Magna Medica is a medical journal of APKKM contains papers and scientific articles created as a form of realization Tridharma college. The journal is published every six months, April and October of three articles in the form of: - Research article - Case report - Literature review The scope of this ...