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All Journal MAGNA MEDICA: Berkala Ilmiah Kedokteran dan Kesehatan
Isnaini Isnaini
[Scopus ID: 57204801189] FK Universitas Lambung Mangkurat, Banjarmasin, South Kalimantan, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Diabetic Wound Healing Activity of Anabas testudineus Fish Scales Erwin Rosadi; Lia Yulia Budiarti; Bhisma Ridho Romadhon; Nida Nurkhalishah; Nur Salsabila Apriliani Risma Putri; Nur Azmina Aisyah; Isnaini Isnaini
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 10, No 1 (2023): February
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.10.1.2023.40-47

Abstract

Background:  Anabas testudineus fish scales are part of the fish that has not been used optimally. Fish scales contain chitin. Chitin which undergoes deacetylation, produces chitosan. Chitosan is an efficacious compound for antibacterial and diabetic wound healing.Objective: This study aimed to extract chitosan from fish scales and test the diabetic wound healing activity of fish scale extract gelMethods: Extraction of fish scales using 0.3 M NaOH, 0.55 M HCl, and 50% NaOH. FTIR will analyze the extraction results to see the functional groups of the extract. Activity test of fish scale extracts diabetic wound healing gel was carried out on Rattus novergicus Wistar strain for 14 days. There were five treatments: negative control, positive control given octenillinR, and fish scale extract gel conc. 5%, 10%, and 15%.Results: The results showed that the fish scales extract contained chitosan, and gel extract fish scale conc 5% have diabetic wound healing activity better than 10% and 15%. Conclusion: A. testudineus fish scale extract contains chitosan, as seen from the FTIR results.
Herbal - Synthetic Drug Interactions Kintoko Kintoko; Aghnia Nabila Ananda; Anisa Rifka Ridho; Annisa Camellia Makati; Asti Afrida Yanti; Dina Wahyuni; Yolanda Sajjida Maghfirah; Isnaini Isnaini
MAGNA MEDIKA: Berkala Ilmiah Kedokteran dan Kesehatan Vol 10, No 2 (2023): August
Publisher : Universitas Muhammadiyah Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/magnamed.10.2.2023.211-220

Abstract

Background:  Herbal medicine is currently one of the therapeutic options chosen by the community because it is considered relatively safer and has minimal side effects. Not only used as a single drug, but herbal ingredients can also be combined with synthetic drugs. However, using herbal and synthetic drugs simultaneously can cause a variety of interactions, including synergism, antagonism, and additive effects (potentiation).Objective: Therefore, it is crucial to do a literature study on the reaction of various herbal medicines to unwanted synthetic drugs to prevent the adverse effects that can be caused.Methods: The literature review is processed based on academic journals published on NCBI, PubMed, and online journal sources that discuss the interactions between herbal medicines and synthetic drugs from 1997 to 2022.Results: Herbal drug interactions can be avoided or managed by providing correct patient advice based on reliable information.Conclusion:The main basic principles of administering these medicines include the doctor's full awareness of the effects and interactions between herbal medicines and herbal medicines and herbal medicines with synthetic drugs. 
Co-Authors Aghnia Nabila Ananda Anisa Rifka Ridho Annisa Camellia Makati Asti Afrida Yanti Bhisma Ridho Romadhon Dina Wahyuni Erwin Rosadi Kintoko, Kintoko Lia Yulia Budiarti Nida Nurkhalishah Nur Azmina Aisyah Nur Salsabila Apriliani Risma Putri Yolanda Sajjida Maghfirah