Background: Management of pain in labor is identified as one of the most important topics related to pregnancy and childbirth. Acupressure and birthing ball exercise are one of the non-pharmacological methods of managing labor pain to help mothers cope with the labor process. This management can relieve pain sensations by increasing the woman's well-being, comfort, and sense of control in labor. This study aims to estimate the effect of acupressure and birthing ball exercise on labor pain.Subjects and Method: This was a systematic review and meta-analysis conducted using PRISMA flow diagrams. Search articles through journal databases including: PubMed, Science Direct, Google Schoolar and SpingerLink by selecting articles published in 2010-2021. The key
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