Majalah Ilmiah METHODA
Vol. 10 No. 3 (2020): Majalah Ilmiah METHODA

BRAIN NATRIURETIC PEPTIDE (BNP) SEBAGAI BIOMARKER GAGAL JANTUNG KONGESTIF

Budi Darmanta Sembiring (Universitas Methodist Indonesia)
Jekson Martiar Siahaan (Universitas Methodist Indonesia)

Article Info

Publish Date
31 Dec 2020

Abstract

Brain Natriuretic Peptide (BNP) is mainly secreted by the heart ventricles and acts as an antagonist to Renin-Angiotensin-Aldosterone. BNP is secreted as pre-proBNP which is broken down into BNP and proBNP in circulation. The BNP examination is done by measuring the levels of BNP or N-Terminal-proBNP depending on the method and the manufacturer. Increased levels of BNP and NT-proBNP indicate heart failure so that BNP and NT-proBNP are considered markers of heart failure. This examination is also indicated to help establish the diagnosis, monitoring, and prognosis of heart failure. Natriuretic peptide examination can be done by several methods such as radioimmunoassay (RIA), Enzyme immunoassay (EIA), Fluorescence immunoassay (FIA), and Sandwich Electro Chemiluminescence Immuno Assay (Sandwich ECLIA).

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Journal Info
Majalah Ilmiah METHODA
Website

Abbrev

methoda

Publisher

Universitas Methodist Indonesia

Subject

Agriculture, Biological Sciences & Forestry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Languange, Linguistic, Communication & Media Medicine & Pharmacology Public Health

Description

Majalah Ilmiah METHODA adalah jurnal ilmih yang dikelola oleh Lembaga Penelitian dan Pengabdian Pada Masyarakat Universitas Methodist Indonesia yang menampung artikel ilmiah dari berbagai multi disiplin ilmu. Majala Ilmiah METHODA terbit 3 kali dalam setahun yakn pada bulan April, Agustus dan ...