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PENYULUHAN MELAHIRKAN GENERASI EMAS KEPADA MASYARAKAT DESA LUMBAN PEA TIMUR, KABUPATEN TOBA Jekson Martiar Siahaan; Juli Jamnasi; Juli Y. Mega; Laura Octavina Siagian; Lesmana Syahrir; Lylys Surjani; Maestro B. U. Simanjuntak; Paul S. M. L. Tobing; Suryati Sinurat; Tengku M. Fauzi; Eka Samuel P. Hutasoit; Jan Pieter Sihombing; Hadyanto Lim; Hendrika A. Silitonga; Ronald T. H. Tambunan; Menang Bastanta Tarigan; Salomo G. U. Simanjuntak; Sumihar M. R. Pasaribu; Putri C. Eyanoer; Dina Riani Purba; Yohanna Agustina Sinaga
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 2 No 1 (2022): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (906.228 KB) | DOI: 10.46880/methabdi.Vol2No1.pp70-73

Abstract

Community Service (PkM) is carried out by the Faculty of Medicine Universitas Methodist Indonesia by providing counselling how to prepare the Gold Generation. PkM was held on 8-11 June 2022 at Lumban Pea Timur, Balige,Toba District, North Sumatera. The method used is to provide counselling/lectures and provide motivation, then followed by question and answer to obtain results and solutions as a form of solving problems and obstacles faced. The results of PkM with counselling are very effective considering that there are still many people who do not get information about the meaning of Gold Generation. With this counselling, the public becomes aware of the Gold Generation. Thus, it is hoped that the people of Lumban Pea Timur will aware and know how to prepare the Gold Generation for their community
TUMOR SUPRESOR GEN p53 SEBAGAI TARGET PENGOBATAN “CANCER” Jekson Martiar Siahaan; Tengku Muhammad Fauzi
Majalah Ilmiah METHODA Vol. 11 No. 1 (2021): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (442.845 KB) | DOI: 10.46880/methoda.Vol11No1.pp10-13

Abstract

The p53 protein functions as a biological molecule that breaks the cycle of damage to DNA damage, even the important function of this molecule is to check whether the organ cells are complete or damaged. However, p53 can undergo mutations that will instead be an oncogene. One way to deal with this is gene therapy, namely PRIMA-1 (p53 Reactivation and Induction of Massive Apoptosis). Until now, further studies are still needed on the effectiveness of this therapy
BRAIN NATRIURETIC PEPTIDE (BNP) SEBAGAI BIOMARKER GAGAL JANTUNG KONGESTIF Budi Darmanta Sembiring; Jekson Martiar Siahaan
Majalah Ilmiah METHODA Vol. 10 No. 3 (2020): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (837.223 KB) | DOI: 10.46880/methoda.Vol10No3.pp130-138

Abstract

Brain Natriuretic Peptide (BNP) is mainly secreted by the heart ventricles and acts as an antagonist to Renin-Angiotensin-Aldosterone. BNP is secreted as pre-proBNP which is broken down into BNP and proBNP in circulation. The BNP examination is done by measuring the levels of BNP or N-Terminal-proBNP depending on the method and the manufacturer. Increased levels of BNP and NT-proBNP indicate heart failure so that BNP and NT-proBNP are considered markers of heart failure. This examination is also indicated to help establish the diagnosis, monitoring, and prognosis of heart failure. Natriuretic peptide examination can be done by several methods such as radioimmunoassay (RIA), Enzyme immunoassay (EIA), Fluorescence immunoassay (FIA), and Sandwich Electro Chemiluminescence Immuno Assay (Sandwich ECLIA).
TINJAUAN BIOMOLEKULER DAN KLINIS OCULAR COVID-19 Lylys Surjani; Jekson Martiar Siahaan
Majalah Ilmiah METHODA Vol. 10 No. 2 (2020): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (402.386 KB) | DOI: 10.46880/methoda.Vol10No2.pp53-66

Abstract

The clinical manifestations of Covid -19 are not only in the airway but are also found in eyes with conjunctival epithelium and ACE-2 receptors as their entry points. The most common clinical manifestation is conjunctivitis, therefore it is not easy to make a diagnosis if it relies on clinical findings because it is similar to a common viral infection. This infection has clinical manifestations in the airway that triggers the immune response leading to a cytokine storm with fatal consequences. There is no specific treatment up to this time. The most important thing is to prevent infection.
ALVEOLAR SOFT PART SARCOMA Sanggam B. Hutagalung; Jekson Martiar Siahaan
Majalah Ilmiah METHODA Vol. 8 No. 3 (2018): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol8No3.pp7-13

Abstract

Alveolar Soft Part Sarcoma (ASPS) is a rare sarcoma, this sarcoma accours around 0,2 – 0,9% of all soft tissue sarcomas. This tumour can occur at any age, but the peak incidence is in the age range of 15 – 35 years, rarely under the age of 5 years and after the age of 50 years. In adults, ASPS most often occur in deep soft tissues in the lower extremites, especially the anterior part of the thighs and buttocks. But in children and infants these tumours often occur in the area of the head and neck, especially the tongue and eyes. Tumours that occur in the head and neck are usually smaller in size may be due to earlier detection. Diagnostic of ASPS can be through CT – Scan/MRI examination, Fnab Citology, Histopathology, and Immunophenotype.
PATOFISIOLOGI GASTROPATI NSAID Salomo Garda Utama Simanjuntak; Jekson Martiar Siahaan
Majalah Ilmiah METHODA Vol. 8 No. 2 (2018): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol8No2.pp73-82

Abstract

NSAIDs are first line therapy for arthritis and widely used in cases of trauma, postoperative pain and other aches. But in the use of NSAID drugs whether it is needed as an analgesic or as an anti-inflammatory all have more or less side effects on the gastrointestinal. The occurrence of side effects of NSAIDs on the gastrointestinal tract can be caused by the direct toxic effects of NSAIDs on the gastric mucosa so the mucosa becomes damaged. While the systemic effect is due to the ability of NSAIDs to inhibit the work of COX-1 which catalyzes the formation of prostaglandins. Prostaglandins in the gastrointestinal mucosa function to maintain mucosal integrity, regulate blood flow, mucous secretion, bicarbonate, epithelial proliferation, and mucosal resistance to damage. The clinical spectrum of NSAID gastropathy includes a wide range of clinical conditions, ranging from the mildest form of gastrointestinal discontrol. Endoscopically mucous congestion will occur, small erosions sometimes accompanied by bleeding
PEDOMAN DALAM PENANGANAN KANDIDIASIS Jadeny Sinatra; Jekson Martiar Siahaan
Majalah Ilmiah METHODA Vol. 8 No. 1 (2018): Majalah Ilmiah METHODA
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methoda.Vol8No1.pp50-61

Abstract

Candida species is an important cause of nosocomial infection that lead to death and prolonged hospital stay. The number of immunocompromised patients, at greater risk of fungal infection, treated in intensive care units (ICUs) has increased considerably. The widespread use of invasive monitoring , therapeutic equipment and treatment with broad spectrum antibiotic increases the risk of fungal colonization and infection. An acute awareness of the increasing incidence of Candida as a pathogen and of the associated morbidity and mortality is necessary. Guidelines management of candidiasis by Infectious Disesase Society of America(IDSA) in 2009 previously, was revised. There have been new data pertaining to diagnosis, prevention, and treatment for proven or suspected invasive candidiasis, leading to significant modification in treatment recommendations, which released in 2016. This article provides a summary of the most recent guideline for the management of candidiasis.
PENYULUHAN PEMBERDAYAAN MASYARAKAT DALAM PENCEGAHAN STUNTING DESA AJIJULU, KABUPATEN KARO Jekson Martiar Siahaan; Hendrika Adriana Silitonga; Hadyanto Lim; Sumihar M. R. Pasaribu; Menang Bastanta Tarigan; Juli Jamnasi; Jadeny Sinatra; Salomo Garda Utama Simanjuntak; Budi Darmanta Sembiring; Edwin Anto Pakpahan; Sanggam B. Hutagalung; Suryati Sinurat; Gita Sradha Br. T. Tambun; Enggrek Pelita Hakim
Jurnal Pengabdian Pada Masyarakat METHABDI Vol 3 No 1 (2023): Jurnal Pengabdian Pada Masyarakat METHABDI
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/methabdi.Vol3No1.pp11-14

Abstract

Community Service (PKM) conducted by the Faculty of Medicine at the Indonesian Methodist University provides counseling on stunting prevention. PKM was held on April 14-16 2023 in Ajijulu Village, Tigapanah District, Karo Regency, North Sumatra. Lectures, discussions and motivations are used as orientation methods. Question and answer discussions were held with the aim of gaining insight, understanding and solutions to solve the problems and limitations faced by the local community. The results of the PKM suggestions and research are very effective, considering that there are still many people who are ignorant of stunting prevention. This counseling increases public awareness about stunting prevention. Residents of Ajijulu must be aware and know the importance of preventing stunting, starting from the time of pregnancy and the first 1000 days of life for toddlers.