Jurnal Kesehatan Farmasi
Vol 4, No 2 (2022)

Uji Efek Analgetik Ekstrak Etanol Bunga Kecombrang (Etlingera elatior. jack) Terhadap Mencit Putih Jantan (Mus musculus)

Fita Selonni (AKADEMI FARMASI PRAYOGA PADANG)
Tuty Taslim (Unknown)



Article Info

Publish Date
29 Dec 2022

Abstract

Background : Ibuprofen is a drug that is commonly used when the body experiences pain. In this study, the medicinal plant that will be tested for its analgesic effect on mice is Kecombrang flower. Methods: Kecombrang flowers were first used as ethanol extract with two different concentrations, namely 400 mg/kgBb and 800 mg/kgBb. The experimental animals used were 20 male white mice which were divided into 4 groups where each group consisted of 5 mice. Each group of mice was given a dose treatment first, then 30 minutes after that, 1.1% acetic acid solution was given via ip, after that, pay attention to the amount of writhing shown by the mice. Results: From the 2 concentrations of kecombrang flower ethanol extract given, it turned out that the 400 mg/kgBb dose group showed fewer stretches than the 800 mg/kgBb dose group, but the analgesic effect was still low compared to the control group + namely ibuprofen. Key words : Kecombrang flower, analgesic and mice

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