<![CDATA[This study aimed to ascertain how students' understanding of reproduction system concepts was impacted by the CLIS (Children Learning Science) learning model combined with flyer media. This was a quasi-experimental study with a non-equivalent control group design. The population consisted of students in six classes of grade XI at SMA Negeri 3 Polewali. Purposive sampling was utilized in the sampling process to obtain XI IPA 3 as a control class and XI IPA 4 as an experimental class. The instrument used to collect the data was a concept accomplishment test, including a pretest and posttest. The data were analyzed using descriptive and inferential statistics. The results showed that the t value was 5,517 and the t table was 1,668. The test results obtained were tcount > ttable (5,517 > 1,668). The test result showed that 5,517 > 1,668, tcount > ttable. As an outcome, at a significant level of 5% (= 0.05), Ha was accepted and Ho rejected. It appears that the CLIS learning model, in combination with media flyers, affects students' understanding of biological concepts related to the reproduction system. The research implication is that the CLIS learning model, combined with the flyer media expected to enhance students' conceptual understanding, can be utilized by educators and can also be used as a resource by subsequent researchers.]]>
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