Usadha
Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional

Obat Herbal Berbasis Bukti Untuk Hepaprotektor: Obat Herbal Berbasis Bukti Untuk Hepaprotektor

Ni Putu Dewi Agustini (a:1:{s:5:"id_ID"
s:34:"Universitas Mahasaraswati Denpasar"
})
Ni Luh Kade Arman Anita Dewi (Fakultas Farmasi Universitas Mahasaraswati Denpasar)
Fitria Megawati (Fakultas Farmasi Universitas Mahasaraswati Denpasar)
Ratna Wulandari (Fakultas Farmasi Universitas Mahasaraswati Denpasar)

Article Info

Publish Date
31 Dec 2022

Abstract

Liver damage can occur due to infection, viruses, drug use, and the environment. Paracetamol is a drug that has analgesic and antipyretic effects, but on the other hand the use of paracetamol in excessive doses (15/day) can cause liver damage. This can occur because the process of paracetamol metabolism in the liver forms a reactive metabolite known as N-acetyl-pbenzoquinonemine (NAPQI). The hepatoprotective mechanism can be seen from the ability of Ichnocarpus frutescens to ward off free radicals formed from the process of lipid oxidation due to the reactive metabolite of paracetamol, namely NAPQI. The method used is a literature review which is a systematic, explicit and reproducible method for carrying out identification, evaluation and synthesis of research works and ideas that have been produced by researchers and practitioners. The data base used is National and International Journal Websites such as Google Scholar.

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Journal Info
Usadha
Website

Abbrev

ushada

Publisher

Universitas Mahasaraswati

Subject

Agriculture, Biological Sciences & Forestry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Description

Usadha: Jurnal Integrasi Obat Tradisional, bertujuan untuk mendorong integrasi Obat Tradisional ke dalam sistem pelayanan kesehatan modern dalam bentuk pertukaran informasi ilmiah baik di kalangan peneliti, praktisi obat tradisional dan tenaga medis, pemegang kebijakan, industri dan stakeholder ...