Jurnal Ilmu dan Teknologi Kesehatan
Vol 11 No 1 (2023): September 2023

Correlation of C-Reactive Protein (CRP) Levels with D-Dimer Levels in COVID-19 Patients

Churiyyah Eka Choirunisa (Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Jakarta III, Indonesia)
Retno Martini Widhyasih (Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Jakarta III, Indonesia)
Rizana Fajrunni’mah (Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Jakarta III, Indonesia)



Article Info

Publish Date
30 Sep 2023

Abstract

Coronavirus disease 2019 is caused by SARS-CoV-2 infection. COVID-19 causes increased levels of proinflammatory cytokines, so CRP and d-dimer levels in COVID-19 patients tend to increase. This study aimed to analyze the correlation between C-Reactive Protein (CRP) levels and D-dimer levels in COVID-19 patients. This research method is analytic observational by using cross-sectional secondary data. The population of this study were all COVID-19 inpatients at Budhi Asih Hospital, East Jakarta, with a sample of 338 patients and were taken by random sampling. The results of this study found that female and male COVID-19 patients had the same risk of being infected with female patients as much as 52,7% and male patients amounting to 47,3%. Most COVID-19 patients occurred at the age of ≥60 years, namely 32,2%. All patients, which is 100% patients had high CRP levels, with a mean of 76,06 mg/L. As for D-dimer levels, 47,9% of patients had normal D-dimer levels and 52,1% had high D-dimer levels with an average of 721,48 ng/mL. The results of the Spearman's correlation test obtained a p value = 0,000, so it can be seen that there is a correlation between C-Reactive Protein (CRP) levels and D-dimer levels in COVID-19 patients with a correlation strength of 0,300 (medium). An increase in CRP levels followed by an increase in D-dimer levels but evaluation of other laboratory examination parameters also needs to be considered.

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Journal Info

Abbrev

jitek

Publisher

Subject

Computer Science & IT Health Professions

Description

Jurnal Ilmu dan Teknologi Kesehatan provides a forum for publishing the novel technologies and knowledge related to the health ...