Indonesian Journal of Pharmaceutical Education
Vol 3, No 3 (2023): September-Desember 2023

Formulasi dan Evaluasi Mutu Fisik Sediaan Masker Gel Peel-Off Ekstrak Biji Pinang (Areca Catechu L.) Sebagai Antioksidan

Asaddah Dwi Mulyani (Jurusan Farmasi, Fakultas Farmasi, Universitas Setia Budi, Surakarta, Indonesia)
Mamik Ponco Rahayu (Jurusan Farmasi, Fakultas Farmasi, Universitas Setia Budi, Surakarta, Indonesia)
Nur Aini Dewi Purnamasari (Jurusan Farmasi, Fakultas Farmasi, Universitas Setia Budi, Surakarta, Indonesia)



Article Info

Publish Date
19 Sep 2023

Abstract

Antioxidants are compounds that can reduce free radicals. Antioxidant compounds in the form of synthetic compounds and natural compounds. One of the plants with antioxidant activity is areca nut (Areca catechu L.). Areca seed extract contains secondary metabolites such as flavonoids, triterpenoids, tannins and has potential antioxidant activity. This study aims to determine the differences in PVA base concentration variations on the physical quality and stability tests of peel-off gel mask preparations and the antioxidant activity of piji areca nut (Areca catechu L.) extract.  This study used areca nut powder which was macerated using 96% ethanol. Areca seed extract is made into a formulation for peel-off gel masks using a PVA base with various concentrations of 10%, 12%, and 14%. Testing the physical quality of the gel peel-off mask preparations included organoleptic tests, homogeneity, pH, viscosity, spreadability, adhesion, dry time, and stability tests. Antioxidant testing of mask preparations was carried out using a UV-Vis spectrophotometer at a wavelength of 516 nm. The research results were analyzed using SPSS on the One Way ANOVA method and independent t test. The results showed that areca seed extract can be formulated into a gel peel-off mask preparation with good physical quality. Formula 2 is a gel peel-off mask preparation which has good physical quality. Antioxidant activity in formula 2 has an IC50 value of 71.789 ppm which is a strong antioxidant.

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Journal Info

Abbrev

ijpe

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology

Description

ndonesian Journal of Pharmaceutical Education (IJPE) adalah junal resmi yang diterbitkan oleh Jurusan Farmasi Universitas Negeri Gorontalo yang bekerja sama dengan IAI (Ikatan Apoteker Indonesia) Provinsi Gorontalo. Artikel pada jurnal ini dapat diakses dan unduh secara online oleh publik (open ...