SRIWIJAYA JOURNAL OF MEDICINE
Vol. 6 No. 1 (2023): Vol 6, No. 1, 2023

GLUT4 as A Protein Target for Type 2-Diabetes Mellitus Therapy With Natural Compounds

Vivi Hendra Sutandar (Biomedical Science Master Program, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Mgs. Irsan Saleh (Department of Pharmacology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)
Ziske Maritska (Department of Biology, Faculty of Medicine, Universitas Sriwijaya, Palembang, Indonesia)

Article Info

Publish Date
20 Feb 2023

Abstract

WHO reported 1.9 million death cases of diabetes patients in 2019. Diabetes is caused by damage in the pancreas which resulted in a lack of insulin or insulin resistance.  Medication for Type 2-Diabetes Mellitus (T2DM) mainly focuses on lowering blood glucose and treating affected organs. Current medications are still lacking; thus research is needed in finding novel medications to accommodate T2DM. This paper aims to present the current research on potential plant extract in increasing GLUT4 translocation in diabetes conditions. insulin resistance state affecting GLUT4 translocation which is important in affecting glucose uptake. Some research shows that plant extract proved to be potential in increasing the translocation of GLUT4 and helping lowering blood glucose levels.

Copyrights © 2023




Citation Download
RIS
EndNote, Reference Manager, ProCite
BibTex
Latex, Jabref
Original Source
Download Original
Google Scholar
Check in Google Scholar
Journal Info
SRIWIJAYA JOURNAL OF MEDICINE
Website

Abbrev

UnsriMedJ

Publisher

Universitas Sriwijaya

Subject

Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Description

Sriwijaya Journal of Medicine (SJM) is a scientific journal managed by Faculty of Medicine Universitas Sriwijaya, Indonesia. It publishes original research articles and reviews in Biomedical Sciences, Medicine (Neurology, Cardiovascular, Respiratory, Gastrointestinal, Urogenital, Endocrine and ...