Journal of Pharmaceutical and Sciences.
JPS Volume 7 Nomor 1 (2024)

Uji toksisitas akut ekstrak rotan sel (Daemonorop melanochaetes Bl.) terhadap larva udang (Artemia Salina Leach) dengan metode brine shrimp lethality test (BSLT)

Athaillah Athaillah (Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia)
Roqayyah Maulida Lubis (Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia)
Putra Chandra (Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia)
Aswan Pangondian (Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia)
Robiatun Rambe (Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia)

Article Info

Publish Date
22 Feb 2024

Abstract

Cell rattan is very popular because it has properties in treating malaria, diabetes and also has appetite-stimulating properties. The chemical content of rattan consists of flavonoids, alcohol, triterpenoids, saponins and glycosides. Flavonoids consist of 15 carbon atoms with a C6-C3-C6 structure. In plants, flavonoids are bound to sugars in the form of flavonoid glycosides and aglycones. Research methods include making rattan extract using the maceration method, phytochemical screening, toxicity activity testing using the BSLT (Brine Shrimp Lethality Test) method and determining the LC50 value based on the probit value. The research results show that rattan extract contains secondary metabolite compounds, including steroids/triterpenoids, saponins, flavonoids, glycosides and alkaloids. The results of the toxicity activity test showed that the LC50 value was 322 ppm and was included in the toxic category.

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Journal Info
Journal of Pharmaceutical and Sciences.
Website

Abbrev

jps

Publisher

Universitas Tjut Nyak Dhien

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Description

Journal of Pharmaceutical and Sciences (JPS) with e-ISSN: 2656-3088 is a scholarly peer-reviewed open access journal related to Pharmaceutics, Pharmacology, biotechnology, Pharmacognosy & Phytochemistry, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Pharmacy practice, Pharmacogenomics, ...