Prominentia Medical Journal
Vol 4 No 2 (2023): Prominentia Medical Journal

FARMAKOGENOMIK: PENDEKATAN FARMAKOLOGI MENUJU PERSONALISED MEDICINE

Jefman Efendi Marzuki HY (Departemen Farmakologi, Fakultas Kedokteran Universitas Surabaya, Surabaya, Indonesia)
Anggi Gayatri (Departemen Farmakologi dan Terapeutik, Fakultas Kedokteran Universitas Indonesia, Jakarta, Indonesia)



Article Info

Publish Date
20 Nov 2023

Abstract

One of the factors contributing to patient morbidity and death is variable variability in treatment response. Adverse drug responses (ADRs) or subtherapeutic effects are possible in certain patients during medication administration. The genetic variation is one of the many variables that contribute to this condition. Pharmacogenomics is the study of how genes influence an individual's response to drugs. The goal of pharmacogenomics is to optimise treatment for the patient. It has been established that a number of genes are associated with drug response, which affects both the direct effects of drugs (pharmacodynamics) and their blood levels (pharmacokinetics). Modifications to a medication's pharmacokinetics and pharmacodynamics may result in toxicity or lessen its efficacy. In order to increase the precision of pharmacotherapy techniques, this study aims to elucidate the availability of data on genetic variants that are known to affect medication response.

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Journal Info

Abbrev

PMJ

Publisher

Subject

Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

Description

Focus and Scope PMJ (Prominentia Medical Journal) is a scientific journal focused on Medicine and Health. PMJ publishes Research Articles, Literature Reviews, and Case Reports that focus on Preventive Medicine and the Prevention of Lifestyle Diseases. Publication Frequency PMJ (Prominentia Medical ...