AbstractNanochloropsis oculata is one of kind green algae that overload in Indonesia ocean. The purpose of this research was to know the potency antioxidant of Nannochloropsis oculata extract as in the Humback Grouper. The research was conducted by experimently and used direct random sampling as design with 4 experiments and 3 repeats i.e control fish, fish was added Nannochloropsis oculata extract, Vibrio alginolyticus - infected fish, and Vibrio alginolyticus - infected fish that was added Nannochloropsis oculata extract. The result showed, fish that added by Nannchloropsis oculata extract made a different influence which was very clear to the decreasing of free radical in the body. Free radical (malonaldehid) in the Vibrio alginolyticus - infected fish was 4, 04 µg/100 mg which fish was added by Nannochloropsis oculata extract, the free radical level was decrease into 3, 29 µg/100 mg massa.
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