Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga.
Vol. 20 No. 1 (2024): June 2024

The Effect Of Butterfly Pea Flower Tea On Brain Weight In Wistar Rats After D-Galactose Induction

Ernadita Budiastuti (Unknown)
Yanasta Yudo Pratama (Unknown)
Miranti Dewi Pramaningtyas (Unknown)
Muhammad Luthfi Adnan (Faculty of Medicine, Universitas Islam Indonesia)



Article Info

Publish Date
12 Jul 2024

Abstract

Introduction: Butterfly pea flowers (Clitoria ternatea L.) currently popular in society as high-antioxidant supplement. One of the organs affected by aging is the brain. D-galactose is a compound that is widely used for induction of aging in animal studies. The aim of this study was to assess the effect of butterfly pea flower tea on changes in brain weight in mice induced by D-galactose. Method: 24 rats were divided into four groups consisting of control, groups with 1%, 5%, and 10% butterfly pea flower tea intervention after being induced by aging for 6 weeks. The brain organs were then weighed to assess changes in each group. Result: There was an increase in body weight but no significant differences between each group either before or after the intervention. No significant differences were found in the average brain weight of each group, with the brain weight of the P3 group being lower than that of the other intervention groups. There is a positive correlation between body weight and brain weight. Conclusion: Although the butterfly pea flower has no statistically significant effect, at concentrations of 1% and 10% it can have an effect on brain weight after induction of aging by D-galactose.

Copyrights © 2024






Journal Info

Abbrev

sainmed

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

Journal of Saintika Medika is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health. This journal publishes original articles, reviews, ...