Jurnal Natural
Volume 24 Number 2, June 2024

Antibacterial, antioxidant and total flavonoid of Adenostemma lavenia (L.)

ZEBUA, NILSYA FEBRIKA (Unknown)
FUJIKO, MUFLIHAH (Unknown)
DACHI, KANNE (Unknown)
NERDY, NERDY (Unknown)
SEPTAMA, ABDI WIRA (Unknown)



Article Info

Publish Date
29 Jun 2024

Abstract

Adenostemma lavenia (L.) is one of the medicinal plants on Nias Island that is used to treat many symptoms including cough, fever and diarrhea. Empirical data of this plant suggests that these medicinal benefits can be attributed to its antibacterial and antioxidant properties, as well as the total flavonoids contained within it, but research on this is still limited. Adenostemma lavenia (L.) was extracted with ethanol, while the antibacterial properties were measured using the disc method. Antioxidant testing was conducted with the DPPH (1,1-diphenyl-2-2picrihydrazyl) inhibition method. Total flavonoids were assessed using a modified AlCl3 method with a quercetin standard. Antibacterial test results of Staphylococcus aureus, Klebsiela pneumoniae, Propionibacterium acnes, Escherichia coli, Salmonella typhi, Bacillus cereus and Shigella sonnei with mean inhibition were 8.76 ± 0.44, 8.13 ± 0.72, 8.77 ± 0.45, 6.47 ± 0.54, 7.77 ± 0.60, 7.33 ± 0.44, 12.06 ± 0.60 respectively. IC50 was 59.844 ± 3.36 ppm. Total flavonoids were 13.566 ± 0.021 mcg/g. The results of the antibacterial test of the ethanolic extract of Adenostemma lavenia (L.) were classified as moderate. The antioxidant activity and total flavonoids were in the high category, which can be attributed to the capture of free radicals to overcome disease.

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Journal Info

Abbrev

natural

Publisher

Subject

Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemistry Earth & Planetary Sciences Energy Immunology & microbiology Neuroscience Physics

Description

Jurnal Natural (JN) aims to publish original research results and reviews on sciences and mathematics. Jurnal Natural (JN) encompasses a broad range of research topics in chemistry, pharmacy, biology, physics, mathematics, statistics, informatic and ...