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All Journal JURNAL PENELITIAN SAINTIKA Science and Technology Indonesia Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Jambura Journal of Health Sciences and Research Jurnal Dunia Farmasi Indonesian Journal of Pharmaceutical and Clinical Research Journal of Pharmaceutical and Health Research Jurnal Indah Sains dan Klinis Journal of Fundamental and Applied Pharmaceutical Science FORTE JOURNAL Mejuajua Jurnal Sains dan Teknologi Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Jurnal Natural Journal of Pharmaceutical and Sciences.
Nilsya Febrika Zebua, Nilsya Febrika
Faculty Of Pharmacy, Universitas Tjut Nyak Dhien, Medan, 20123, Indonesia
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PLIKASI VISUAL BASIC.NET DALAM PENENTUAN DOSIS OBAT PASIEN HIPERTENSI KOMPLIKASI GAGAL GINJAL Usman, Ari; Zebua, Nilsya Febrika
JURNAL PENELITIAN SAINTIKA Vol 18, No 1 (2018): MARET 2018
Publisher : JURNAL PENELITIAN SAINTIKA

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Abstract

Hipertensi atau darah tinggi merupakan kondisi tekanan darah yangmeningkat secara berkelanjutan melebihi batas normal. Hipertensi dapatmengakibatkan terjadinya gagal ginjal yaitu menurunnya fungsi ginjal yang ditandai dengan nilai bersihan kreatinin dan ureum yang tinggi. Pasien gangguan ginjal harus mendapatkan dosis obat berdasarkan perhitungan bersihan kreatinin ginjalnya untuk menghindari terjadinya toksisitas obat akibat kegagalan ekskresi oleh ginjal. Penelitian ini mengaplikasikan bahasa pemograman Visual Basic.Net (VB.NET) dalam perhitungan dosis obat individual berdasarkan rumus farmakokinetik untuk pasien hipertensi komplikasi gagal ginjal di Rumah Sakit Dr. Pirngadi Medan. Berdasarkan aplikasi Visual Basic.Net (VB.Net) perhitungan dosis obat pada pasien hipertensi diperoleh 6 dari 9 kasus penggunaan ranitidin, 8 dari 13 kasus penggunaan kaptopril, dan 2 dari 2 kasus penggunaan digoksin. Aplikasi Visual Basic.Net untuk menghitung dosis obat individual mudah digunakan dan sangat membantu dalam menetapkan dosis obat pada pasien yang menderita gangguan ginjal.
THE UTILIZATION OF CORN COB´S CRACKER AS ANTICIPATION OF HARVEST FAILURE FOR ECONOMIC IMPROVEMENT FOR FARMER IN NARIGUNUNG 1 VILLAGE, KARO REGENCY Putra, Effendy De Lux; Yuliasmi, Sri; Prasetyo, Bayu Eko; Zebua, Nilsya Febrika
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 2 (2018): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (680.428 KB) | DOI: 10.32734/abdimastalenta.v3i2.4123

Abstract

Narigunung 1 village is one of the villages located in Tiganderket District, Karo Regency, and North Sumatra Province. The community in this village consists of 150 heads of households whereby 90% earn a living by farming. The community manages various kinds of horticulture plants, especially vegetables and fruits, i.e. corn. The Geographic Village, which is located near to (± 8 km) the bottom of Sinabung mount, causes people often get crop failures, since the hot wind released from the Sinabung mount. Especially at the dry season, since the village is far from the source of water, therefore only relies on rain drops both for daily needs and for their agricultural lands. Failure of this harvest can reduce the economic welfare level of the community in the village. This community service activity was carried out, with the aim to stimulate the farmers and the community in Narigunung 1 village to make cracker businesses as a means of improving community welfare. The activity was carried out in the form of lectures, discussions, practice of making crackers from corn cobs, dissemination of food additives that were good for health, and the distribution of modules. After this service activity, the community in Narigunung 1 has been able to make crackers by utilizing corn cob which increases the economic value of the corn cob, using a grinding machine as a transfer knowledge of science and technology in the community and gain comprehensive knowledge about additional ingredients that are good for health.
THE UTILIZATION OF CORN COB´S CRACKER AS ANTICIPATION OF HARVEST FAILURE FOR ECONOMIC IMPROVEMENT FOR FARMER IN NARIGUNUNG 1 VILLAGE, KARO REGENCY Putra, Effendy De Lux; Yuliasmi, Sri; Prasetyo, Bayu Eko; Zebua, Nilsya Febrika
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 3 No. 2 (2018): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (680.428 KB) | DOI: 10.32734/abdimastalenta.v3i2.4123

Abstract

Narigunung 1 village is one of the villages located in Tiganderket District, Karo Regency, and North Sumatra Province. The community in this village consists of 150 heads of households whereby 90% earn a living by farming. The community manages various kinds of horticulture plants, especially vegetables and fruits, i.e. corn. The Geographic Village, which is located near to (± 8 km) the bottom of Sinabung mount, causes people often get crop failures, since the hot wind released from the Sinabung mount. Especially at the dry season, since the village is far from the source of water, therefore only relies on rain drops both for daily needs and for their agricultural lands. Failure of this harvest can reduce the economic welfare level of the community in the village. This community service activity was carried out, with the aim to stimulate the farmers and the community in Narigunung 1 village to make cracker businesses as a means of improving community welfare. The activity was carried out in the form of lectures, discussions, practice of making crackers from corn cobs, dissemination of food additives that were good for health, and the distribution of modules. After this service activity, the community in Narigunung 1 has been able to make crackers by utilizing corn cob which increases the economic value of the corn cob, using a grinding machine as a transfer knowledge of science and technology in the community and gain comprehensive knowledge about additional ingredients that are good for health.
Test of Burn Wounds Healing Effects of Collagen From Snakehead Fish (Channa striata) Bone in The Preparation of Cream on Male White Rats (Rattus norvegicus) Hasri, Najwa Miladi; Zebua, Nilsya; Sudewi
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 3 No. 1 (2020): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v3i1.3977

Abstract

Abstract. The use of snakehead fish (Channa striata) collagen in cream is an alternative toreduce fish wastes. It has been proved that snakehead fish (Channa striata) contain collagen.This research aims to study the burn wound healing effectivity of bone’s collagen fromsnakehead fish (Channa striata) that is formulated into a cream. This study used theexperimental method with the bone of snakehead fish (Channa striata) as a sample. This studyconsisted of 4 (four) such as isolation of collagen from snakehead fish's (Channa striata) bone,characterization of collagen by analyzing moisture, ash, protein, fat and functional groupanalysis with FTIR, formulation, and evaluations of cream such as organoleptic test,homogeneity test, pH measurement, stability test, and irritation test, and burn wound healingtest in male white rats (Rattus norvegicus) and the result is analyzed using SPSS 22.0 Free trialand One Way ANOVA and Post-Hoc Tukey HSD. The results showed that fish collagen couldbe isolated from snakehead fish (Channa striata) and the yield obtained is 33.3%. The results ofcollagen characterization and evaluation test met the collagen standard requirements. Results ofthe burn wound healing test on male white rats (Rattus norvegicus) showed that K1 burn woundrecovered on day 21, K2 on day 12, K3 on day 15, K4 on day 18, and K5 on day 18.Measurement of burn wound diameter on day 21 showed K1 = 1.20 cm, K2 = 0.15 cm, K3 =0.10 cm, K4 = 0.45 cm, K5 = 0.40 cm. The results of the statistical analysis of burn wounddiameter showed a significant difference p = 0,000 (p <0.05) between each group. K3 showedthe reduction in the burn wound diameter is faster and the smallest, it can be concluded that theoptimal dose of snakehead fish bone’s collagen cream is a concentration of 3%.
Comparison Between The Suspension and Capsule Preparation from Waste of Avocado Seeds As Antidiarrhea in Induced Mouse Saputri, Muharni; Zebua, Nilsya Febrika; Asih, Fivi Nur; Putri, Ghera Fakhira
Journal of Fundamental and Applied Pharmaceutical Science Vol 2, No 2 (2022): February
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v2i2.13504

Abstract

Diarrhea is one type of disease with the most sufferers every year. Thus, it is considered an endemic disease in Indonesia and the potential disease of Extraordinary Events accompanied by mortality. One of the plants that can be used as a traditional medicine for diarrhea is the avocado seed, as it contains tannins, alkaloids, flavonoids, steroids and glycosides, which act as antidiarrheals. This study aims to determine the antidiarrheal effect of avocado seed extract suspension on mice induced by Oleum ricini and the optimum concentration of avocado seed extract suspension and capsules with an antidiarrheal effect in white male mice induced by Oleum ricini. The dosage forms chosen were suspension and capsules. This study used an experimental method with a test sample of the avocado seed. Avocado seed Simplicia was extracted by the percolation method, then an oral suspension and capsule formulation were made from the avocado seed methanol extract. It was evaluated and tested for its effectiveness with mice to cure diarrhea. Normal data were analyzed by One Way ANOVA and Post Hoc Tuckey Method. The results of this study showed that the administration of a suspension of avocado seed methanol extract at a dose of 800 mg/KgBB had the most optimum effect as an antidiarrheal against white male mice with a stool weight of 0.39 grams and a duration of diarrhea for 74 minutes. Furthermore, the administration of avocado seed extract capsules at a dose of 75 mg/KgBB had the most optimum effect as antidiarrheal against white male mice with Loperamide as a positive control. Therefore, it can be concluded that all suspension formulations and capsules of avocado seed methanol extract met the requirements for preparation evaluation. Suspension and avocado seed methanol extract capsules can cure diarrhea in white male mice.
Formulasi Sediaan Krim Menggunakan Kolagen Tulang Ikan Patin (Pangasius sp.) sebagai Anti Aging Sudewi Sudewi; Nilsya Febrika Zebua; Shelva Filiana Sari
Journal of Pharmaceutical and Health Research Vol 1 No 2 (2020): Juni 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (350.09 KB)

Abstract

Patin fish (Pangasius sp.) is a fish that has been cultivated by many people because it has a high content of omega 3. People consume patin fish meat as a source of protein, while patin fish bones are only disposed of as waste. Collagen is a protein derivative that has the effect of maintaining skin elasticity. This study aims to determine whether the patin fish bones contain collagen and is there an influence of the use of anti-aging collagen patin fish bone cream on the results of changes in facial skin care. Collagen characterization using infrared spectrophotometry and formulated into cream preparations with concentrations of 1%, 1,5%, 2,5%, 3,5% and evaluation of preparations include homogeneity test, pH measurement, emulsion type determination test, stability test, skin irritation to volunteers and anti-aging effectiveness test. The results showed that patin fish bones contained collagen at wave numbers 3250-3350 cm-1 and 1260-1630 cm-1 which indicated the presence of amine and amide groups. The use of patin fish collagen cream affects the changes in texture, wrinkles, moisture, blemishes and pores become smoother. The best formulation is the formula that contains 3,5% of patin fish bone collagen
Formulasi Sediaan Krim Menggunakan Kolagen Tulang Itik Serati (Cairina Moscahta) Sebagai Anti Aging Nilsya Febrika Zebua; Nurul Anggraini; Sudewi Sudewi
Journal of Pharmaceutical and Health Research Vol 1 No 2 (2020): Juni 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

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Abstract

At the age of 30, humans lose about 15-20% of collagen and at the age of 40, humans no longer produce collagen, so additional collagen is needed from outside the body. Serati duck bone (Cairina moschata) has not been treated yet and is a waste. This study aims to determine the presence of collagen content in serati duck bones (Cairina moschata) and to formulate serati duck collagen in cream preparations as anti-aging. This study used an experimental method, using serati duck test material (Cairina moschata). Stages of research include extraction of collagen from serati duck bone (Cairina moschata), characterization of collagen with Infrared Spectrophotometry, manufacturing of serati duck bone collagen cream (Cairina moschata) with concentrations of 1%, 1.5%, 2.5%, 3.5% and evaluation of collagen cream preparations. The results showed that the serati duck bone (Cairina moschata) contained collagen at wave numbers 2920-3280 cm-1 and 1270 - 1630 cm-1 indicating the presence of amine and amide groups. Serati duck collagen can be formulated into an oil-emulsion (M / A) type of cream emulsion with the results of evaluation of the preparation is a homogeneous and stable preparation for 12 weeks of storage, does not irritate the skin, and the pH range of 6.0 to 6.3. Statistical test results show a probability smaller than 0.05. The results of the test of anti-aging cream preparations on the face showed changes in large pores to small, changes in many blemishes to a little and changes in wrinkled skin to become wrinkled. Anti aging cream preparations have shown a significant increase in effect every week for a month using this anti aging cream
Formulasi Sediaan Krim Menggunakan Kolagen Tulang Itik Air (Anas platyrhynchos domesticus) Sebagai Anti Aging Sudewi Sudewi; Nilsya Febrika Zebua; Aulia Milda
Journal of Pharmaceutical and Health Research Vol 1 No 3 (2020): Oktober 2020
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (391.172 KB) | DOI: 10.47065/jharma.v1i3.615

Abstract

The collagen content in the human body decreases with age. One solution to reduce these negative effects is the application of collagen in various cosmetic and medicinal products. In the bones contain a lot of collagen and one of them is found in the water duck bone that has not been treated and is the result of waste. This study aims to make an anti- aging cream preparation resep from water duck bone collagen that can eliminate wrinkles, blemishes, shrink pores and smooth the skin. This research uses an experimental method using water duck bone test material. Stages of research include extraction of collagen from water duck bone, collagen characterization by infra red spectrophotomenter, making anti- aging cream of water duck bone with concentrations of 1%, 1. 5%, 2. 5%, 3. 5%, formulation and evaluation of cream preparations and test the ability of preparations using a skin analyzer. The results showed that the water duck bone contained collagen at wave numbers 3280- 3380 cm- 1 and 1280- 1680 cm- 1 which indicated the presence of amine and amide groups. Water duck bone collagen can be formulated into cream preparations with the evaluation results of preparations are homogeneous, stable and non- irritating preparations with a pH range of 6. 1 to 6. 4. Test results from collagen cream preparations show that the higher the concentration of collagen added to the resep, the more it will show a significant increase in effect.
Formulasi Sediaan Hand Body Lotion Menggunakan Ekstrak Etanol Daging Buah Kedondong (Spondias dulcis Soland. ex Forst. fil.) Sebagai Pelembab Kulit Sudewi Sudewi; Yessi Febriani; Siti Raudah; Ira Nofriani; Nilsya Febrika Zebua
Journal of Pharmaceutical and Health Research Vol 2 No 2 (2021): Juni 2021
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v2i2.861

Abstract

Kedondong fruit (Spondias dulcis Soland. Ex Forst. Fil.) Is a fruit plant originating from South and Southeast Asia and spread in tropical areas. Kedondong fruit contains vitamins A, B and C, carbohydrates, protein and fat. This study aims to determine the pulp of kedondong (Spondias dulcis Soland. Ex Forst. Fil.) In the form of ethanol extract which can be formulated into a hand body lotion which at certain concentrations can provide a moisturizing effect on the skin and is not irritating. This research was conducted using experimental methods, using the test material of the pulp of the kedondong fruit (Spondias dulcis Soland. Ex Forst. Fil.). The ethanol extract of kedondong pulp (Spondias dulcis Soland. Ex Forst. Fil.) Was obtained by maceration using 96% ethanol filter, then concentrated using a rotary evaporator. The preparation is formulated into a hand body lotion with a concentration of 0.5%, 1.5%, 2.5% and 3.5%, as well as a blank. Examination of the physical quality of the preparation includes, homogeneity test, pH test, emulsion type test, stability test, irritation test and effectiveness test of the preparation in moisturizing the skin and comparing with preparations on the market using the Skin Moisturer Checker (AramÒ) and statistical data processing was carried out using the SPSS 26.00 ANOVA method. The results showed that the pulp of kedondong (Spondias dulcis Soland. Ex Forst. Fil.) In the form of ethanol extract can be formulated into a hand body lotion, a homogeneous preparation with the type of oil-in-water emulsion (M / A), has a momentary pH range. After making 6,6-7,3 and pH after 12 weeks of storage 6,3-7,0, the effectiveness test of moisture preparation at a concentration of 3.5% (Formula E) gave moisture (32%) categorized as "moist" which was statistically showed a significant difference with the comparison results, the hand body lotion that was made did not irritate the skin.
Pengenalan dan Pencegahan Hipertensi Serta Pengecekan Tekanan Darah : Pengenalan dan Pencegahan Hipertensi Serta Pengecekan Tekanan Darah di Mesjid Al-Karim, Desa Sari Laba Jahe, Kecamatan Sibiru-Biru, Kabupaten Deli Serdang Eva Sartika Dasopang; Nilsya Febrika Zebua; Syarifah Nadia; Ernawaty Ginting; Dessy Natalia Siahaan; Muharni Saputri; Ika Julianti Tambunan; Muflihah Fujiko; Siti Rahmi Ningrum; Dea Anggraini; Fenny Hasanah; Anna Juniar
Mejuajua: Jurnal Pengabdian pada Masyarakat Vol. 1 No. 2 (2021): Desember 2021
Publisher : Yayasan Penelitian dan Inovasi Sumatera (YPIS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (474.322 KB) | DOI: 10.52622/mejuajuajabdimas.v1i2.11

Abstract

Hipertensi merupakan kondisi medis dengan prevalensi tinggi, dimana merupakan suatu sindrom atau kumpulan gejala kardiovaskuler yang progresif sebagai akibat dari kondisi lain yang kompleks dan saling berhubungan. Banyak masyarakat yang belum menyadari pemicu hipertensi adalah dari pola hidup sehari-hari yang salah. Maka perlu di berikan informasi dan edukasi sehingga masyarakat dapat mengenal dan mencegah penyakit hipertensi sejak dini. Sehingga prevalensi terhadap hipertensi akan menurun. Metode penyampaian informasi dan edukasi yang disampaikan yaitu dengan cara persentase. Hasil kegiatan ini meningkatkan pengetahuan masyarakat terhadap penyakit hipertensi
Co-Authors Afni Saufa Yarda Anna Juniar Ari Usman Ari Usman, Ari Asih, Fivi Nur Aulia Milda CHRISTICA ILSANNA SURBAKTI dafitri salsabila Dea Anggraini Dessy Natalia Siahaan EFFENDY DE LUX PUTRA Effendy De Lux Putra, Effendy De Lux Ernawaty Ginting Ernawaty Ginting Eva Sartika Dasopang Faisal Yusuf Fekbri Yanti Fenny Hasanah Hafizurrahman Hafizurrahman Hasri, Najwa Miladi Ika Julianti Tambunan Ika Julianti Tambunan Ira Nofriani JIHAN SAFIRA Kanne Dachi Khalisa Khalisa Khoiriyah Khairul Linda Margata Masrina Prihatini Meutia Indriana Mey Linda Hasibuan Muflihah Fujiko Muflihah Fujiko Muflihah Fujiko Muharni Saputri Nerdy, Nerdy Nia Zulkarnain Nurmala Sari Nurmala Sari Nurul Anggraini Nurul karima Nurul Karimah Prasetyo, Bayu Eko Pravil Mistryanto Tambunan Puji Lestari Putri, Ghera Fakhira Qalbiah Nurmilad B Rahma Yulia Rahma Yulia Reza Novriansyah Rina Ridara Riska Julia Safriana Rosniwaty Br. Bangun Said Haikal Alfajar salmah handayani Lubis salman salman Saputri, Muharni Shadiq Suwailim Shelva Filiana Sari Siti Aisyah Siti Arum Widiyanti siti muliani julianty Siti Rahmi Ningrum Siti Raudah Siti Salmiyah Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sudewi Sulika Hati Sumardi Sumardi Supran Hidayat Supran Hidayat Supran Hidayat Syarifah Nadia Syarifah Nadia syarifah nadia maulina Tandra Alexandro Tari Putri Utami Rizki Tedy Kurniawan Bakri Tedy Kurniawan Bakri Virda Widya Pratiwi Vonna Aulianshah Vriezka Mierza Yessi Febriani Yuliasmi, Sri Yuliasmi, Sri Yuni Syafitri