Jurnal Ilmiah Kedokteran Wijaya Kusuma
Vol 3, No 1 (2014): Edisi Maret 2014

MANGOSTEEN SKIN EXTRACTS DECREASE THE ACTIVITY OF THE GAMMA-GLUTAMYLTRANSFERASE (-GT) SERUM ON THE CIGARETTE EXPOSURE

Raharjo, Loo Hariyanto (Unknown)
Santoso, Hwa Tjeen Anna Lewi (Unknown)



Article Info

Publish Date
12 Jun 2017

Abstract

Exposure to cigarette smoke can cause oxidative stress, which characterized by increased activity of g-GT serum. The skins of the mangosteen (Garcinia mangostana L.) contain anthocyanins pigments, which can act as antioxidants to reduce free radicals. This study mainly aims to investigate the effect of mangosteen skin extracts to decreased activity of g-GT serum in rats exposed to cigarette smoke. This study was true experimental designs with randomized post-test only control group design. This study used thirty male rats were dividing into six treatment groups. Rats exposed to cigarette smoke, which came from two cigarettes, for 4 weeks lead to an increase free radicals in the body. The increased activity of g-GT serum to damp the free radicals. Mangosteen skin extracts can reduce free radicals so that the activity of g-GT serum decreased.The conclusion of this research is the mangosteen skin extracts can decrease the activity of the g-GT serum.

Copyrights © 2014






Journal Info

Abbrev

JIKW

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

Description

Jurnal Ilmiah Kedokteran Wijaya Kusuma (JIKW) is a periodically scientific publication that contains articles written in Indonesia or english. JIKW receive articles in the scope of Biomedical Sciences, degenerative diseases, infections, congenital abnormalities and public health. JIKW published ...