Paediatrica Indonesiana
Vol 52 No 5 (2012): September 2012

Prevalence of urinary tract infection in 2-8-week-old infants with jaundice

Partini Trihono (Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta)
Arfianti Chandra Dewi (Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta)
Hartono Gunardi (Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta)
Hanifah Oswari (Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta)



Article Info

Publish Date
31 Oct 2012

Abstract

Background Urinary tract infections (UTI) in infants may manifest in various ways and often appear without symptoms. Previous studies have reported that j aundice has been observed in infants aged less than 8 weeks 'With UTIs. However, a prospective study on the prevalence of UTI in infants with jaundice aged 2􀁂8weeks is warranted in order to improve diagnosing capability and provide prompt treatment.Objective To investigate the prevalence and profiles of UTI in infants with jaundice aged 2􀁂8 weeks.Methods This cross􀁂sectional study was carried out in June-December 2011 in infants with jaundice aged 2􀁂8 weeks. Subjects were patients from the Department of Child Health, Cipto Mangunkusumo Hospital (CMS), as well as the Pediatric Polyclinics ofBudi Kemuliaan and Thamrin Hospitals. All subjects underwent total, direct and indirect bilirubin examinations, urinalyses and urine cultures.Results Of the 110 subjects recruited, the prevalence of UTI was 18.2%. More boys than girls had UTIs (13 boys, 7 girls). The microorganisms found in subjects v.ith UTIs were Escherichia coli (10/20), Klebsiella pneumoniae (8/20), and Enterobacter aerogenes (2120). Indirect hyperbilirubinemia was found in 5/20 subjects. There were more subjects with UTIs in the non􀁂exclusively breastfed (8/20) and non􀁂breastfed (8/20) groups than in the exclusively breastfed group (4/20), the full term gestational age (GA) group (17/20) than the pretenn GA group (3/20), and the normal birth weight group (15/20) than the low birth weight group (5/20). The median age of jaundice onset was 3.5 days (range lAO days), and the median duration of jaundice was 13.5 days (range 3-56 days).Conclusion The prevalence of UTI in infants aged 2􀁂8 weeks v.ith jaundice was 18.2%. More boys than girls had UTIs. The most common infecting microorganism found in our subjects was Escherichia coli. In daily medical practice, infants with prolonged jaundice of more than 2 weeks should be tested byurin alysis and urine cultures for the presence of UTIs. [Paediatr Indones.2012;52:304-8].

Copyrights © 2012






Journal Info

Abbrev

paediatrica-indonesiana

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of ...