Majalah Obat Tradisional
Vol 21, No 2 (2016)

AKTIVITAS ANTELMINTIK BIJI Veitchia merrillii TERHADAP Ascaridia galli SECARA IN VITRO

Abdullah Hamzah (Faculty of Veterinary Medicine, Syiah Kuala University)
Muhammad Hambal (Faculty of Veterinary Medicine, Syiah Kuala University)
Ummu Balqis (Faculty of Veterinary Medicine, Syiah Kuala University)
Darmawi Darmawi (Faculty of Veterinary Medicine, Syiah Kuala University)
Maryam Maryam (Post Graduate Program of Veterinary Public Health, Syiah Kuala University)
Rosmaidar Rosmaidar (Faculty of Veterinary Medicine, Syiah Kuala University)
Farida Athaillah (Faculty of Veterinary Medicine, Syiah Kuala University)
Muttaqien Muttaqien (Faculty of Veterinary Medicine, Syiah Kuala University)
Azhar Azhar (Faculty of Veterinary Medicine, Syiah Kuala University)
Ismail Ismail (Faculty of Veterinary Medicine, Syiah Kuala University)
Rastina Rastina (Faculty of Veterinary Medicine, Syiah Kuala University)
Eliawardani Eliawardani (Faculty of Veterinary Medicine, Syiah Kuala University)



Article Info

Publish Date
31 Aug 2016

Abstract

The objective of this research was to evaluate the anthelmintic activity of ethanolic extract of nuts Veitchia merrillii against intestinal nematode, Ascaridia galli. Phytochemical tests were performed for testing different chemicals group present in the extract. The effect of these extract were determined by in vitro based on inhibition of motility and mortality of worms. Amount of four worms were exposed in triplicate to each of phosphate buffered saline, 25 mg/mL, and 75 mg/mL crude ethanolic extract of V. merrillii, and 15 mg/mL albendazole. The motility of worm was observed on 9, 18, 27, and 36 hours interval. The mortality of worms were recognized by their straight flat appearance with no movements at the head and tail regions of the body. We found that the ethanolic extract of V. merrillii contains tannins, alkaloids, flavonoids, triterpenoids, and saponins neither steroid. Based on the in vitro trials conducted using above extract at 25 and 75 mg/mL concentration, the extract of V. merrillii showed anthelmintic effect. The extract of V. merrillii was effective at 75 mg/mL concentration only. The study indicated that it is potential to develop herbal-based anthelmintic to control A. galli in poutry.

Copyrights © 2016






Journal Info

Abbrev

TradMedJ

Publisher

Subject

Health Professions Medicine & Pharmacology Public Health

Description

raditional Medicine Journal (Majalah Obat Tradisional), or Trad. Med. J. (ISSN 1410-5918 (print) and ISSN 2406-9086 (online)), is an international scientific journal published by Faculty of Pharmacy, Universitas Gadjah Mada, three times annually. Collaborating with Indonesian Pharmacist Association, ...