Research Journal of Life Science
Vol 4, No 3 (2017)

Black Grass Jelly (Mesona Palustris Bl) Effervescent Powder has Anti-Dyslipidemia in High Cholesterol Diet-Fed Rats and Antioxidant Activity

Dian Handayani (Department of Nutrition, Faculty of Medicine, University of Brawijaya)
Tri Dewanti Widyaningsih (Department of Food Science and Technology, Faculty of Agricultural Technology, University of Brawijaya)
Novita Wijayanti (Department of Food Science and Technology, Faculty of Agricultural Technology, University of Brawijaya)
Mey Etika (Department of Food Science and Technology, Faculty of Agricultural Technology, University of Brawijaya)



Article Info

Publish Date
12 Jan 2018

Abstract

Dyslipidemia that could be affected by hypercholesterol diet is a contributing factor in millions of deaths worldwide and a risk factor for ischemic heart disease and stroke. High soluble fiber diet is used as one of the non-pharmacological treatments to control hypercholesterolemia. Black Grass Jelly (Mesona palustris BL) also known as black cincau has a high soluble fiber content. This study aimed to investigate the effect of black cincau as effervescent powder form (BCEP) for anti-dyslipidemia and also the antioxidant activity. BCEP was orally administered to twenty male dyslipidemia Wistar rats induced with hypercholesterol diet for 3 weeks then plasma lipid profile was measured using enzymatic CHOD-PAP assay. The antioxidant activity also has been identified. Oral administration of 3 different doses of BCEP resulted in lipid profiles by decreasing plasma cholesterol (TC), triacylglycerol (TG), low-density lipoprotein (LDL), and also high-density lipoprotein (HDL) in dyslipidemia rats (α =  0.01). The increasing doses of BCEP revealed that it has a potential effect of decreasing plasma lipid.

Copyrights © 2017






Journal Info

Abbrev

RJLS

Publisher

Subject

Education

Description

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