Indonesian Journal of Biotechnology
Vol 21, No 1 (2016)

Evaluation of antimicrobial activity and identification of yellow pigmented marine sponge-associated fungi from Teluk Awur, Jepara, Central Java

Mada Triandala Sibero (Department of Coastal Resources Management, Faculty of Fisheries and Marine Science, Diponeggoro University, St. Imam Bardjo, SH., Semarang 50241, Central Java, Indonesia)
Desy Wulan Triningsih (Laboratory of Marine Natural Product, Integrated Laboratory of Diponegoro University, St. Prof. Soedarto, SH., Tembalang, Semarang 50269, Central Java, Indonesia)
Ocky Karna Radjasa (Department of Coastal Resources Management, Faculty of Fisheries and Marine Science, Diponeggoro University, St. Imam Bardjo, SH., Semarang 50241, Central Java, Indonesia)
Agus Sabdono (Department of Marine Science, Faculty of Fisheries and Marine Science, Diponegoro University, St. Prof. Soedarto, SH., Tembalang, Semarang 50269, Central Java, Indonesia)
Agus Trianto (Department of Marine Science, Faculty of Fisheries and Marine Science, Diponegoro University, St. Prof. Soedarto, SH., Tembalang, Semarang 50269, Central Java, Indonesia)

Article Info

Publish Date
01 Jun 2016

Abstract

Marine sponge associated fungi are known as potential source of metabolites with various biological activities. Natural pigment is one of metabolite which produced by microorgisms. Several researches reported the antimicrobial activity from natural pigment. Unfortunatelly there are lack of information about marine fungi natural pigment and its producer. The aims of this research were to identify yellow pigmented Indonesian marine sponge-associated fungi, to extract the pigment, and to study the antimicrobial activity of the pigment against clinical MDR bacteria and clinical pathogenic fungi. Sponge associated-fungus isolate MT23 was successfully identified as Trichoderma parareesei. The fungal pigment could be extracted only in methanol with yield 6,22±0,29%. The pigment could inhibitted S. typhi and E. coli MDR strains. The biggest antibacterial activity was shown by concentration 1000µg/mL against S. typhi with inhibition zone was 4.03±0.06 mm.

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Journal Info
Indonesian Journal of Biotechnology
Website

Abbrev

ijbiotech

Publisher

Universitas Gadjah Mada

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Materials Science & Nanotechnology

Description

The Indonesian Journal of Biotechnology (IJBiotech) is an open access, peer-reviewed, multidisciplinary journal dedicated to the publication of novel research in all aspects of biotechnology, with particular attention paid to the exploration and development of natural products derived from ...