Objective: To determine predictive factors for pregnancy after
IVF.
Method: The subject of this study were three hundred and forty
eight IVF cycles in 266 couples who underwent controlled ovarian
hyperstimulation in IVF cycles between January 2005 and March
2010. Categorical variables were compared using Chi Square test
and continuous variables were analyzed using Independent t-test, p
< 0.05 was considered statistically significant. Multivariate logistic
regression analysis was done to test correlations between clinical
variables and the occurrence of pregnancy.
Results: The womenâs age significantly influenced pregnancy
rate since women under 35 years old has the best chance for pregnancy
(56.4%). Endometrial thickness on the day of hCG administration
also significantly influenced pregnancy in IVF (p < 0.001)
because 64.1% of pregnancy occurred if endometrial thickness â¥
10.95 mm. Serum FSH on 3rd day of period that can predict ovarian
reserve also has significance on pregnancy. On the other hand,
61.5% pregnancy occurred if more than 6 mature oocytes were retrieved
(p < 0.001). Among 92 patients of 348 cycles we found
strong correlation between AMH level with number of mature oocytes
retrieved (p < 0.001; r 0.659). Logistic regression done revealed
the couple with best chance of pregnancy can be described
as follows: women with endometrial thickness ⥠10.95 mm, number
of mature oocytes > 6 and age under 35 years old.
Conclusion: This study enabled the characterization of many
prognostic factors for pregnancy.
[Indones J Obstet Gynecol 2010; 34-4: 180-4]
Keywords: in vitro fertilization, clinical pregnancy, age, mature
oocytes, endometrial thickness
Copyrights © 2010