Health Notions
Vol 2, No 1 (2018): January

Bee Pollen Effect on Blood Glucose Levels in Alloxan-induced Male Wistar Rats

Aprilia Nurcahyaning Rahayu (Department of Public Nutrition, Faculty of Public Health, Airlangga University)
Bambang Wirjatmadi (Department of Public Nutrition, Faculty of Public Health, Airlangga University)
Merryana Adriani (Department of Public Nutrition, Faculty of Public Health, Airlangga University)
Soenarnatalina M. (Department of Biostatistics and Population, Faculty of Public Health, Airlangga University)
Dwi Winarni (Department Biology, Faculty of Science and Technology, Airlangga University)
Sri Hartiningsih (Faculty of Medicine, Hang Tuah University)

Article Info

Publish Date
31 Jan 2018


Bee pollen, as an active ingredient in diabetes mellitus (DM) prevention and treatment, is able to reduce oxidative reactions and to regenerate cells. This study aimed to determine bee pollen effect on blood glucose levels of rats which induced by alloxan. This study used a completely randomized design with Pre-Post Test design and Control Group design. The subjects were 25 male wistar rats which divided randomly into 5 groups: (1) negative control group (non-DM rats); (2) positive control group (DM rats without bee pollen); (3) P1 group (DM rats with 0.25 g/day bee pollen); (4) P2 group (DM rats with 0.63 g/day bee pollen); and (5) P3 group (DM rats with 1.25 g/day bee pollen). Alloxan inducing was used to cause rats under DM or hyperglycemic conditions. The data were analyzed by Manova test and Tukey HSD test. Statistical analysis showed that bee pollen effectively had an effect on decreasing fasting blood glucose (FBG) levels in treatment groups with 0.002. Differences test showed a difference between positive control group and treatment groups, but there was no difference between all treatment groups. However, the bee pollen dosage which giving the lowest average of FBG was 0.25 g on P1 group. Keywords: Bee pollen, Blood glucose level, Alloxan

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