Journal of Pharmaceutical and Medicinal Sciences
Vol 2 No 2 (2017): JPMS

Aktivitas Inhibisi Pertumbuhan Plasmodium falciparum dan Micobacterium tuberculosis dari Ekstrak dan Partisi Klika Kayu Jawa (Lannea coromandelica [Houtt.] Merr.)

Nursalam Hamzah (Jurusan Farmasi Fakultas Kedokteran dan Ilmu Kesehatan Universitas Islam Negeri Alauddin)
Nurhidayah Wahid (Jurusan Farmasi Fakultas Kedokteran dan Ilmu Kesehatan Universitas Islam Negeri Alauddin)
Muh Ihsan (Jurusan Farmasi Fakultas Kedokteran dan Ilmu Kesehatan Universitas Islam Negeri Alauddin)
Nur Syamsi Dhuha (Jurusan Farmasi Fakultas Kedokteran dan Ilmu Kesehatan Universitas Islam Negeri Alauddin)
Karnila Amir Tahir (Jurusan Farmasi Fakultas Kedokteran dan Ilmu Kesehatan Universitas Islam Negeri Alauddin)
Alifia Putri Febrianti (Jurusan Farmasi Fakultas Kedokteran dan Ilmu Kesehatan Universitas Islam Negeri Alauddin)
Isriany Ismail (Jurusan Farmasi Fakultas Kedokteran dan Ilmu Kesehatan Universitas Islam Negeri Alauddin)



Article Info

Publish Date
19 Feb 2018

Abstract

Malaria and tuberculosis are two diseases with high prevalence in Indonesia. The treatment has a problem because some types of plasmodium and mycobacterium resistance with antituberculosis and antimalarials which are used today. To solve this problem, exploration to create a new drug must be done. Kayu jawa (Lannea coromandelica [Houtt.] Merr.) is one of the plants commonly used as a traditional medicine for curing malaria and tuberculosis. This research aimed to explore the antimalaria dan antituberculosis of L. Coromandelica. The procedure begins with the extraction of stem bark with methanol, then partitioned by solid-liquid extraction to found soluble and insoluble hexane partitions. Both extract and partitions were tested for anti-plasmodium activity by Desjardins method and antituberculosis by MODS method. The result showed that all samples can inhibit Mycobacterium tuberculosis growth and also Plasmodium falciparum. In conclusion, L. Coromandelica has a potential to developed as antimalaria and antituberculosis drug.

Copyrights © 2017






Journal Info

Abbrev

jpms

Publisher

Subject

Medicine & Pharmacology

Description

The Journal of Pharmaceutical and Medicinal Sciences (JPMS) pISSN 2528-2824; eISSN 2580-328X dedicated to publish original research papers, original research notes, invited topical reviews, mini-reviews, editorial commentary and news. Medicinal resources about exchange of information and ...