Journal of Pharmaceutical and Medicinal Sciences
Vol 2 No 2 (2017): JPMS

Pengaruh Pemberian Perasan Belimbing Wuluh (Averrhoa bilimbi L.) Terhadap Kemampuan Fisik Mencit (Mus musculus) Yang Dipapar Asap Rokok

Agung Giri Samudra (Akademi Farmasi Al-Fatah Bengkulu)
Sari Yanti (Akademi Farmasi Al-Fatah Bengkulu)
Dwi Ani Wijayanti (Akademi Farmasi Al-Fatah Bengkulu)



Article Info

Publish Date
15 Feb 2018

Abstract

One of the plants that are often used to maintain of our healthy body is the star fruit (Averrhoa bilimbi L.), that high contains vitamin C. Cigarette smoke contains harmful substances such as nicotine, tar, and carbon monoxide are the trigger free radicals. The purpose of this study to evaluate the effect of star fruit juice to physical ability of male mice (Mus musculus) against cigarette smoke-induced. Mice were divided into five groups (n=5/group): standard group where Garcia (1.04 mg /20 g BW), was used as standard drug and 3 test groups were given fresh juice of star fruit (0.2 mL, 0,4 mL, 0,6 mL/ 20gram BW) was used for 14 days via gavage through oral route. All groups were exposed to cigarette smoke during treated (1 cigarette per day). The physical ability was assessed on day 15-forced swimming test (FST) has been done in mice. The results showed a strong and dose-dependent prevention effect and significantly exhibited an increase in mean swim endurance time on day 15 compared to baseline (p <0.05). In conclusion, the star fruit juice possesses a protective effect.

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Journal Info

Abbrev

jpms

Publisher

Subject

Medicine & Pharmacology

Description

The Journal of Pharmaceutical and Medicinal Sciences (JPMS) pISSN 2528-2824; eISSN 2580-328X dedicated to publish original research papers, original research notes, invited topical reviews, mini-reviews, editorial commentary and news. Medicinal resources about exchange of information and ...