Jurnal Respirologi Indonesia
Vol 38, No 4 (2018)

The Changes of Interleukin 17 levels On Pulmonary Tuberculosis Patients with AFB Smear-Positive After 2 Months Anti Tuberculosis Drugs Treatment

Andy Sulaiman Siregar (Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Airlangga, RSUD Dr.Soetomo, Surabaya)
Soedarsono Soedarsono (Departemen Pulmonologi dan Kedokteran Respirasi, Fakultas Kedokteran Universitas Airlangga, RSUD Dr.Soetomo, Surabaya)

Article Info

Publish Date
28 Oct 2018

Abstract

Background: Tuberculosis still remain as a health problem in the world. No specific biomarkers can be used to monitor the rapid response to TB therapy. This study aims to assess the change of IL-17 levels in pulmonary tuberculosis patients with AFB smear-positive before and after 2 months of anti tuberculosis drugs (ATD) treatment. Method: Design of study is analytic observational with prospective cohort. The subject include 17 new cases of pulmonary tuberculosis patients with AFB smear-positive in Soetomo Hospital Surabaya from July - October 2016. Plasma levels of IL-17 were measured using ELISA technique before treatment and 2 months after the ATD therapy. Results: The mean levels of IL-17 before treatment is 3.510 pg / ml (2.087- 5.051 pg/ml). There were significantly decreament (p = 0.001

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Journal Info
Jurnal Respirologi Indonesia
Website

Abbrev

jri

Publisher

Perhimpunan Dokter Paru Indonesia

Subject

Health Professions Medicine & Pharmacology

Description

Jurnal Respirologi Indonesia (JRI) is an online and printed scientific publication of the Indonesian Society of Respirology (ISR). The journal is published thrice-monthly within a year (January, April, July and October). The journal is focused to present original article, article review, and case ...