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INDONESIA
Jurnal Respirologi Indonesia
ISSN : 08537704     EISSN : 26203162     DOI : -
Core Subject : Health,
Jurnal Respirologi Indonesia (JRI) is an online and printed scientific publication of the Indonesian Society of Respirology (ISR). The journal is published thrice-monthly within a year (January, April, July and October). The journal is focused to present original article, article review, and case report in pulmonary and critical care medicine.
Arjuna Subject : -
Articles 264 Documents
Effects of Ginseng Extract to The Plasma Level of Interleukin-8, COPD Assessment Test Scores, and Length of Hospitalization Acute Exacerbation of COPD Patients Aslani Threestiana Sari; Suradi Suradi; Jatu Aphridasari
Jurnal Respirologi Indonesia Vol 38, No 4 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1473.848 KB) | DOI: 10.36497/jri.v38i4.20

Abstract

Background: COPD exacerbations is an acute condition with worsening symptoms and require more intensive treatment changes. Increased inflammatory exacerbations marked increase in plasma levels of IL-8, exacerbation of clinical symptoms and risk of hospitalization. Ginseng extracts have anti inflammatory so it can be used as an additional drug in COPD exacerbations. Method: This study aimed to analyze the effect of ginseng extract on plasma levels of IL-8, CAT scores, and length of hospitalization of patients with COPD exacerbations. Clinical trials of experimental with pre test and post test design was conducted on 34 patients with COPD exacerbation in Dr. Moewardi Hospital Surakarta and Dr. Ario Wirawan Lung Hospital Salatiga from August until September 2016. Samples were taken by consecutive sampling were divided into two groups. The treatment group (n = 17) received standard therapy and ginseng extracts 2x100mg/day and the control group received only standard therapy (n = 17). Clinical improvement measured in CAT score and length of stay. Plasma levels of IL-8, CAT scores, and longer hospitalization time measured at entry and discharge criteria are met. Length of stay based on the number of days of care in hospitals. Results: There were significant difference (p=0.000) towards decreased of of IL-8 plasma level between treatment group (-12.38 ± 10,35pg/ml) and control group (0.65 ± 7,92pg/ml), towards decrease of CAT score (p=0.000) between treatment group (-16.53 ± 1.28) and control group (-12.59 ± 2.87), and length of stay (p = 0.004) between treatment group (4.29 ± 1.45) and control group (5.76 ± 1.20). Conclusions: The addition of ginseng extract 2x100 mg/day during hospitalization was significantly lowered plasma levels of IL-8, CAT scores, and shortening the length of stay. (J Respir Indo. 2018; 38: 192-8)
Clinical Profile and Treatment Evaluation of Rifampicin-Resistant and Multidrug-Resistant Tuberculosis Patients at Dr. Kanujoso Djatiwibowo Public Hospital, Balikpapan Randy Adiwinata; Josephine Rasidi; Maurits Marpaung
Jurnal Respirologi Indonesia Vol 38, No 3 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (836.35 KB) | DOI: 10.36497/jri.v38i3.2

Abstract

Background: Rifampicin-resistant (RR-TB) and multidrug-resistant tuberculosis (MDR-TB) remains a major health problem worldwide and in Indonesia also become a challenge in total eradication of tuberculosis. Dr. Kanujoso Djatiwibowo Public Hospital (RSKD) Balikpapan is one of the two referral hospitals in East Kalimantan for evaluation and initiation of MDR-TB treatment. The objective of this study is to evaluate clinical profile and treatment of RR-TB and MDR-TB patients at RSKD. Methods: A retrospective cross-sectional study was conducted using data from eTB manager database and medical record of RR-TB and MDR-TB at RSKD from January 2013 to October 2016. Results: Twenty eight RR-TB and MDR-TB patients, most of them were female (53.6%), belong to 35-44 age group (28.6%), housewife (25%), graduated from senior high school (42,9%), malnutrition (28.6%), and relapse cases (50%). Diabetes mellitus and anemia were found in 42,9% and 44.4% of the patients, respectively. The most resistant pattern is rifampicin-resistant TB (57,1%) followed by rifampicin and isoniazid resistant. The most common side effect of TB treatment was gastrointestinal complaints (44.4%). The success rate of MDRTB treatment at RSKD was 20%, followed by 20% mortality, 50% of lost to follow up, 10% of treatment failure, and there are 8 patients still ongoing therapy. Conclusion: Most of the RR-TB and MDR-TB cases were relapse cases. Counseling, education, and support for the patients undergoing MDR-TB treatment are strongly needed to increase success rate and decreasing number of lost to follow up.
The Role of Thoracic Ultrasound in Diagnosing Pneumothorax Mia Elhidsi; Budhi Antariksa; Dianiati Kusumo Sutoyo
Jurnal Respirologi Indonesia Vol 38, No 4 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (885.155 KB) | DOI: 10.36497/jri.v38i4.48

Abstract

Diagnosis of a pneumothorax in some cases the can be difficult. Traditional gold-standard modalities may not be available or feasible to institute. In this situation, thoracic sonography for pneumothorax can be especially helpful, allowing a method of quickly ruling out this potentially life-threatening complication. Its sensitivity dan specificity of ultrasound is higher than conventional chest x-ray. The four sonograms useful to diagnose pneumothorax and their usefulness in ruling in and ruling out the condition are lung sliding, lung pulse, B-lines and lung point. (J Respir Indo. 2018; 38: 239-43)
Levels of Carbon Monoxide Expiratory Air on Shisha Users and the Factors Affecting Mirsyam Ratri Wiratmoko; Chandrika Karis Adhalia
Jurnal Respirologi Indonesia Vol 39, No 1 (2019)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v39i1.38

Abstract

Background: Shisha is one method of consuming tobacco similar to cigarette but in a different form. Lately it became a trend in Indonesian people, especially teenagers, without knowing any hazards contained in shisha which could cause cancer or even death. Lack of study about shisha in Indonesia was the main reason to do this study so further impact of shisha could be understood. Methodology: This study was analytical observational with cross sectional design. Data of this study was obtained from examination using CO analyzer and from questionnaire filling by respondents from the shisha Bogor community and smokers in Bogor. Results: Among 60 samples we obtained mean expiratory air CO levels of 8,62 ppm for smokers and 20,67 ppm for shisha users. There were also a significant correlation between shisha consumption duration per times and CO expiratory air levels, with P-value of 0,004 and odds ratio 12,52. Conclusion: Expiratory air CO levels in shisha users were higher than smokers, also there were a significant correlation between shisha consumption duration per times and the increasing levels of expiratory air CO. (J Respir Indo 2019; 39(1): 37-43)
The Differences of Respiratory Symptoms and Pulmonary Impairment between Exposure and Unexposured Areas by Dust from Semen Padang Factory Dian Citra; Irvan Medison; Sabrina S Ermayanti
Jurnal Respirologi Indonesia Vol 38, No 3 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (764.837 KB) | DOI: 10.36497/jri.v38i3.7

Abstract

Background: The cement factories have a waste product such as dust that had negative impact on respiratory system. The aims of this study is to investigate the differences of respiratory symptoms and pulmonary impairment between exposure and unexposured region by dust from Semen Padang factory. Methods: Cross sectional study of 282 subjects from exposure and unexposure areas in Semen Padang factory. This study was held in March 2016 - July 2017. Dust levels were assessed at both areas. Respiratory symptoms were assessed by interviews and quistionnaires. Lung function was measured by spirometry examinations. The variables between both groups were analyzed. Results: The daily dust level of exposure area close to three folds than unexposure area (150μg/Nm 3 vs 53,50 μg/Nm 3) yet still in save level that assigned by regulation. There were 282 subjects from both areas which consist of 67 men and 74 women for each area. There were no differences in respiratory symptoms included chest pain (0% vs 0,7%, P=1,00), productive cough (4,3% vs 2,1%, P=0,5), cronic cough (4,3% vs 2,1% ,P=0,5) and breathlessness (5,7% vs 5% ,P=1,00). The proportion of pulmonary impairment not difference between two areas (P=0,053). Concusions: Both area had dust level below up level assigned by regulation. There were no differences in respiratory symptoms and pulmonary impairment at exposure area and unexposure area. Breathlessness is most common symptom.
Students’ Smoking Profile at Sukatani Village, Purwakarta Cindra Paskaria; Fransisca Fransisca; Jeanastasia Kurnia; Zaneth Gunawan; Decky Gunawan
Jurnal Respirologi Indonesia Vol 38, No 4 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1396.974 KB) | DOI: 10.36497/jri.v38i4.21

Abstract

Background: Smoking habits had become a culture in various nations in the world. The World Health Organization (WHO) estimates that tobacco use is responsible for the deaths of about six million people worldwide each year. In Indonesia, 32,1% of students had ever used any smoked tobacco product. Purpose of this study is to analyze smoking profile and CO concentration on students. Method: This study was an observational analytic with cross sectional design. Data collection through survey and CO measurements by smokerlyzer CO breath test on 98 students at Sukatani Village, Purwakarta. Results: The proportion of students who smoking was 45,92%, the existence of smokers role model in the family influenced smoking behaviour in those students OR=5,724 (p=0,001). There was significant difference of CO concentration in each group (active smokers, passive smokers, and non-smokers) with p value
Effect on Ubiquinone MDA Level of Plasma, FEV1% and CAT Score Stable COPD Patients Ardorisye Fornia; Suradi Suradi; Aphridasari Aphridasari
Jurnal Respirologi Indonesia Vol 38, No 3 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (816.362 KB) | DOI: 10.36497/jri.v38i3.3

Abstract

Background: Oxidation stress showed clinical evidence of increased in patients with COPD and contribute functionally to expiratory air flow resistance, so the body requires exogenous antioxidants to inhibit oxidative stress. This study was conducted to assess whether there is influence on levels of MDA plasma ubiquinone, FEV1% and patients with stable COPD CAT score. Methods: This study is a clinical trial experimental with pretest and post-test design which aims to determine the effect of plasma MDA, FEV1% and patients with stable COPD CAT score. Subjects consist of 30 patients with stable COPD who came to Pulmonary outpatient clinic of Moewardi hospital Surakarta during June to August 2016. The sample was taken by consecutive sampling. Subjects were divided into two group, the treatment group (n=15) received additional therapy ubiquinone 1x150mg/day and the control group (n=15) received standard therapy. MDA plasma levels, FEV1% and CAT scores were measured at the time of control pulmonary outpatient clinic. Results: Giving ubiquinone can significantly lower CAT score better in the treatment group compared to the control group. There were no statistically significant difference (p=0.744) in plasma MDA treatment group (1.37 ± 0.11) compared to controls (1,39 ± 0.16). There were no statistically significant difference between (p=0.276) the decline in FEV1% treatment group (43.28 ± 20.59) and the control group (36.01 ± 14.73). Conclusion : The use of Ubiquinone in decreasing CAT score for stable COPD patients. There was lowering effect in MDA plasma but there was no excalation value in FEV1%.
The Association Between Smoking History and Intensive Phase Treatment Success of Pulmonary Tuberculosis Patients in Dr. Zainoel Abidin Hospital Banda Aceh Risa Fitria; Feni Fitriani Taufik; Dewi Behtri Yanifitri
Jurnal Respirologi Indonesia Vol 38, No 4 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (921.127 KB) | DOI: 10.36497/jri.v38i4.47

Abstract

Background: Many diseases are associated with smoking such as malignant disease, cardiovascular, diabetes mellitus (DM), chronic obstructive pulmonary disease (COPD), arthritis, impotence, infertility, Alzheimer’s Disease, tuberculosis and others. Smoking is proven to disrupt the ciliary mucosal clearance and it is associated with an increased risk of pulmonary tuberculosis. Sputum conversion is an important indicator to assess the success of TB treatment. This study aims to determine the relation between smoking history and the success intensive phase treatment of pulmonary tuberculosis at Dr Zainoel Abidin Hospital. Method: Prospective cohort study in patients with pulmonary tuberculosis acid-fast bacilli (AFB) positive (+) smokers and non smokers who visited the Integrated Tuberculosis Care (PTT), at outpatient and inpatient pulmonary infection RSU Dr. Zainoel Abidin hospital Banda Aceh from 28 November 2015 until 1 February 2016. Results: A total of 38 subjects were divided into 2 groups (19 subjects with 19 subjects smokers and non-smokers). All subjects smokers are male while nonsmoker subjects consisted of male and female. The results of the first month study (p=0.009), there are 14 non smoker subjects with AFB conversion (73,7%) and 5 subjetcs without AFB conversion. Among smoking subjects there are 6 subjets (31.6%) with AFB conversion and 13 subjects (68.4% ) without AFB conversion. In the second month (p=0,202), more than half subjects who are non-smokers had AFB conversion, 17 subjects (89.5%) and 2 subjects (10.5%) had no AFB conversion. In smokers group there are 14 subjects (73.7% ) had AFB conversion and 5 subject (26.3%) had no conversion. Conclusion: There was a significant relation between smoking habit and the occurrence of first-month AFB sputum. (J Respir Indo. 2018; 38: 232-8)
Distribution of Lung Cancer Patients in Dharmais Cancer Hospital Year 2008-2012 Fariha Ramadhaniah; Desy Khairina; Dian Triana Sinulingga; Evlina Suzanna; Achmad Mulawarman Jayusman
Jurnal Respirologi Indonesia Vol 39, No 1 (2019)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v39i1.1

Abstract

Background: Lung cancer is the most commonly found cancer. At the population level, the incidence and mortality from lung cancer ranks first among all cancer cases which occur in male and the fourth most common cancer in female, while the survival of lung cancer is very short, namely 13 months. This study describes several variables of lung cancer cases at the Dharmais Cancer Hospital epidemiologically and clinically. Methods: The study was a cross-sectional study using the lung cancer data from 2008-2012 in Dharmais Cancer Hospital with hospital-based cancer registration data sources. Results: Cases of lung cancer in male are three times more common when compared to female and cases begin to increase in the 45-year age group. The location of the tumor was more commonly found in the right lung (48.2%) and adenocarcinoma was the most common type found (41,7%). The cancer stage at the time of the first hospital visit was mostly unknown (60.1%) and bone is the most commonly found (36,4%) metastasis location. Conclusion: The lung cancer location in the right lung, adenocarcinoma type, stage unknown in the first hospital visit and bone metastasis was the most commonly found epidemiology and clinical lung cancer patients in Dharmais Cancer Hospital. (J Respir Indo 2019; 39(1): 31-6)
Neutrophyl Lymphocyte Ratio in Tuberculosis Patients and Multi Drug Resistant Tuberculosis Patients Delores Elisabeth Sormin; Parluhutan Siagian; Bintang YM Sinaga; Putri Chairani Eyanoer
Jurnal Respirologi Indonesia Vol 38, No 3 (2018)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (785.039 KB) | DOI: 10.36497/jri.v38i3.8

Abstract

Background: Delayed in diagnosis and treatment of tuberculosis will increase the risk of MDR TB. WHO recommends Xpert MTB/RIF as diagnostic tools to identify MDR TB. Availability of Xpert MTB/RIF is still limited, another diagnostic tool is needed. Neutrophyl lymphocyte ratio (NLR) was presumed to be able to identify the probability of MDR TB. The aim of this study is to evaluate the comparison of NLR in tuberculosis and MDR TB patients. Methods: This is an analytic descriptive study with case series approach in Adam Malik General Hospital Medan. This study held since January – December 2015 with number of sample as much as 100 bacteriological confirmed TB patients and 100 MDR TB patients. We performed leukocyte differential count from peripheral blood examination to obtain NLR Result: Mean NLR of TB patient 4.62±2.37 and MDR TB 3.28±1.44. There was significant difference of NLR between both groups using Mann-Whitney test (P=0.001). The cut off value by ROC analysis was 2.91 with sensitivity, specificity, positive predictive value, negative predictive value and accuracy was 77%, 50%, 60.6%, 68.4% and 63.5% respectively. Conclusion: There was significant difference of NLR between bacteriological confirmed TB patients and MDR TB patients. Value of NLR

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