Jurnal Farmasi Higea
Vol 3, No 2 (2011)

Uji Aktivitas Sitotoksik Ekstrak Dan Fraksi Dari Spon Laut Petrosia sp. Dengan Metode Brine Shrimp Lethality Test

Dian Handayani (Fakultas Farmasi Universitas Andalas Padang)
Lendra Yunance (Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang)
Krisyanella Krisyanella (Sekolah Tinggi Ilmu Farmasi (STIFARM) Padang)



Article Info

Publish Date
19 Aug 2016

Abstract

The determination of cytotoxic of the marine sponge Petrosia sp. using Brine Shrimp Lethality Test has been done. The cytotoxic activity analysis were done toward condensed extract, n-hexane, ethyl acetate and butanol fractions  and yielded LC50 value 70.736 ppm, 269.153 ppm, 197.38 ppm and 70.667 ppm respectively. It shown that butanol fraction was more cytotoxic than the other fractions.

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